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Table 3 Direct and indirect effect (mediated by VA) of glycemic variability on in hospital death

From: Glycemic variability and in-hospital death of critically ill patients and the role of ventricular arrhythmias

 

Full association,

OR (95% CI)

Direct association,

OR (95% CI)

Mediated by VA,

OR (95% CI)

Percent mediation, %

P value for indirect effect

Crude

1.76 (1.64–1.89)

1.72 (1.60–1.84)

1.03 (1.02–1.03)

4.41

< 0.001

Adjusted

1.30 (120 − 1.41)

1.29 (1.12–1.40)

1.01 (1.01–1.02)

3.85

< 0.001

  1. Adjusted for age, sex, ICU category, race, sepsis, myocardial infarction, heart failure, cerebrovascular disease, chronic pulmonary disease, malignant cancer, eGFR, serum sodium, potassium, mean arterial pressure, hear rate and average blood glucose