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Table 3 Multivariate Cox regression analysis for MACE

From: The synergistic effect of the triglyceride-glucose index and serum uric acid on the prediction of major adverse cardiovascular events after coronary artery bypass grafting: a multicenter retrospective cohort study

Variables

HR (95% CI)

Model 1

Model 2

Model 3

TyG index

 Per unit increase

1.70 (1.43–2.04)***

1.49 (1.22–1.82)***

1.53 (1.24–1.89)***

 Per SD increase

1.40 (1.25–1.56)***

1.28 (1.13–1.45)***

1.30 (1.14–1.49)***

 TyG ≤ 8.87

1 (Reference)

1 (Reference)

1 (Reference)

 TyG > 8.87

2.42 (1.89–3.10)***

2.14 (1.64–2.79)***

2.18 (1.66–2.86)***

SUA

 Per unit increase

1.00 (1.00–1.01)***

1.00 (1.00–1.01)***

1.00 (1.00–1.01)***

 Per SD increase

1.35 (1.20–1.51)***

1.34 (1.19–1.52)***

1.35 (1.18–1.55)***

 Non-HUA

1 (Reference)

1 (Reference)

1 (Reference)

 HUA

1.90 (1.43–2.51)***

1.87 (1.40–2.50)***

1.84 (1.37–2.49)***

  1. Model 1: Adjusted for age and gender
  2. Model 2: Adjusted for variables with P-value < 0.05 in univariate analysis, including age, LVEF, left main disease, smoking, DM, hypertension, TC, LDL-C and eGFR
  3. Model 3: Adjusted for all the variables in Model 2 plus gender, BMI, drinking, hyperlipidemia, duration of surgery, OPCABG, number of grafts, use of arterial grafts, antiplatelet drugs, statins, hypoglycemic drugs and urate-lowering drugs
  4. TyG index triglyceride-glucose index, SUA serum uric acid, MACE major adverse cardiovascular events, HUA hyperuricemia
  5. ***P < 0.001
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Cardiovascular Diabetology

ISSN: 1475-2840