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Fig. 7 | Cardiovascular Diabetology

Fig. 7

From: Dysregulation of hypoxia-inducible factor 1α in the sympathetic nervous system accelerates diabetic cardiomyopathy

Fig. 7

Increased advanced glycation end products in the left ventricle of diabetic Hif1aCKO hearts. A Representative images of PAS staining of advanced glycation end products (AGEs). Scale bar 50 µm. B Delineated PAS+ area in the LV myocardium by Adobe Photoshop. C PAS+ area was quantified using ImageJ and expressed as a percentage of the area of the LV. Data are mean ± SD (n = 5 hearts per genotype and one section per sample). Statistical significance assessed by two-way ANOVA followed by post hoc Tukey ‘s multiple comparisons test, ***P < 0. 001, ****P < 0.0001. LV, left ventricle

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Cardiovascular Diabetology

ISSN: 1475-2840