Table 1 Baseline characteristics of our patients. Data are means ± SD or n (%). BMI: body mass index. SBP: systolic blood pressure. DBP: diastolic blood pressure. HR: Heart rate. COPD: chronic obstructive pulmonary disease. CKD: chronic kidney disease. HDL: High-density lipoprotein; LDL: Low-density lipoprotein. HbA1c: glycated hemoglobin.
Extended-release Metformin Women | Non-Treated Women | Regular Metformin Women | Extended-release Metformin Men | |
|---|---|---|---|---|
N | 40 | 38 | 36 | 31 |
Age (years) | 77.1 ± 7.8 | 75.6 ± 5.5 | 76.0 ± 5.2 | 75.7 ± 6.0 |
BMI (kg/m2) | 29.5 ± 3.4 | 28.6 ± 3.2 | 29.6 ± 3.6 | 28.5 ± 3.3 |
SBP (mmHg) | 132.8 ± 10.8 | 133.1 ± 12.1 | 131.8 ± 9.5 | 133.4 ± 11.5 |
DBP (mmHg) | 81.8 ± 9.9 | 81.5 ± 10.2 | 81.6 ± 9.0 | 82.0 ± 10.4 |
HR (bpm) | 73.8 ± 9.0 | 73.1 ± 9.0 | 74.5 ± 9.4 | 73.5 ± 8.6 |
Comorbidities | ||||
Dyslipidemia, n (%) | 30 (75.0) | 27 (72.0) | 26 (73) | 22 (71.0) |
COPD, n (%) | 14 (35.0) | 13 (34.0) | 13 (36) | 12 (39.0) |
CKD, n (%) | 15 (37.0) | 15 (39.0) | 14 (39) | 12 (39.0) |
Laboratory parameters | ||||
Plasma glucose (mg/dl) | 160.8 ± 49.1 | 155.3 ± 39.4 | 155.5 ± 40.6 | 156.6 ± 40.4 |
Cholesterol (mg/dl) | 195.2 ± 18.2 | 194.9 ± 18.7 | 193.1 ± 18.8 | 196.0 ± 19.1 |
LDL-cholesterol (mg/dl) | 130.3 ± 16.7 | 130.0 ± 16.5 | 129.6 ± 16.4 | 130.5 ± 16.8 |
HDL-cholesterol (mg/dl) | 39.5 ± 3.6 | 38.9 ± 3.7 | 38.7 ± 3.9 | 39.1 ± 3.4 |
Creatinine (mg/dl) | 1.0 ± 0.2 | 0.9 ± 0.1 | 0.9 ± 0.2 | 0.9 ± 0.2 |
HbA1c (%) | 7.2 ± 0.6 | 7.1 ± 0.7 | 7.1 ± 0.7 | 7.4 ± 0.5 |