Table 3 Association between Metabolites and Cardiovascular Events
All (N = 2218) | Flemengho (N = 1331) | Hortega (N = 887) | ||||||
|---|---|---|---|---|---|---|---|---|
HR (95% CI) * | P | HR (95% CI) | P | HR (95% CI) | P | |||
Factor 2 | 1.22 (1.10–1.36) | 0.0002 | 1.20 (1.05–1.37) | 0.006 | 1.37 (1.24–1.04) | 0.017 | ||
Major represented metabolites | ||||||||
Glucose + glutamine | 1.24 (1.09–1.40) | 0.0007 | 1.23 (1.04–1.45) | 0.016 | 1.45 (1.23–1.02) | 0.031 | ||
Glucose + 2-aminobutyrate | 1.20 (1.06–1.36) | 0.004 | 1.12 (0.94–1.33) | 0.22 | 1.33 (1.25–1.05) | 0.013 | ||
Glucose + 2-phosphoglycerate | 1.19 (1.06–1.35) | 0.005 | 1.15 (0.98–1.35) | 0.079 | 1.35 (1.24–1.02) | 0.030 | ||
Glucose | 1.20 (1.06–1.36) | 0.004 | 1.12 (0.93–1.34) | 0.24 | 1.34 (1.23–1.04) | 0.018 | ||
Unknown molecule | 1.24 (1.09–1.42) | 0.001 | 1.22 (1.01–1.46) | 0.035 | 1.46 (1.27–1.05) | 0.012 | ||
Glycine | 1.04 (0.92–1.18) | 0.51 | 1.03 (0.86–1.24) | 0.75 | 1.24 (1.11–0.92) | 0.27 | ||