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Table 2 Clinical parameters of cohort 1

From: Adipose tissue specific CCL18 associates with cardiometabolic diseases in non-obese individuals implicating CD4+ T cells

Measure

Control (A)

CVD

(B)

T2D

(C)

CVD + T2D

(D)

p-value

ANOVA

(ABCD)

Gender

F/ M

8/9

9/9

4/9

6/9

 

Age

years

58 ± 3

(53–63)

61 ± 4

(55–68)

60 ± 4

(53–66)

60 ± 4

(52–65)

0.227

BMI

kg/m2

26 ± 2

(22–29)

26 ± 2

(22–29)

26 ± 2

(23–30)

27 ± 2

(24–30)

0.114

% FAT DEXA

34.3 ± 7.1 (21.2–45.6)

34.3 ± 9.8 (20.1–45.9)

31.2 ± 7.9 (14.2–41.4)

33.8 ± 6.1 (24–48)

0.793

Abdominal scFAT (ESAT) grams

1066–1607#(970–2446)

1272 ± 480 (689–2168)

900 ± 440 (313–1819)

1043 ± 610 (277–2763)

0.086

P-glucose mmol/l

5.6 ± 0.4

(4.9–6.7)

5.5 ± 0.3

(5.1–6.4)

7.5 ± 1.6

(5.6–10.6)

6-8.8 #

(4.9–20.2)

< 0.0004

HbA1c mmol/mol

35 ± 5

(24–44)

37 ± 2

(33–41)

46 ± 9

(34–67)

42–65 #

(40–84)

< 0.0001

Fat cell volume pl

547 ± 90

(438–770)

406–610 #

(7–1295)

538 ± 178

(336–900)

609 ± 107

(422–758)

0.410

TG

mmol/l

1.1–1.7 #

(0.8–3.4)

0.8–1.2 #

(0.4–3)

0.8–1.6 #

(0.7–3.7)

0.8–2.7 #

(0.5–6.8)

0.232

Cholesterol mmol/l

5 ± 0.7

(4–7.2)

5.1 ± 1.1

(3.2–7.3)

4.1 ± 1.0

(2.6–6.5)

4.1 ± 1.1

(2.6–6.7)

0.006

HOMA-IR

1.3 ± 0.46

(0.6–2.4))

1.2 ± 0.5

(0.5–2.5)

2.5 ± 1.9

(0.4–7.3)

1.2 ± 4.7

(0.3–17.6)

0.025

For normally distributed values, mean ± SD with minimal and maximal values are shown. For non-normally distributed values (indicated with #), median- interquartile range with minimal and maximal values are indicated. One-Way ANOVA was performed for each factor to determine the significant changes between the four groups. Significant values are indicated in bold. For HOMA-IR, statistical tests were performed after transforming the values in log.