Table 1 Summary of cohorts
Cohort | BMI (mean) | Summary of patient characteristics | Measurements available | Assay used in this paper | Reference as in the text |
|---|---|---|---|---|---|
1 | 26.2 | Non-obese men and women with T2D and/or CVD | WAT secretion samples, WAT phenotype, clinical metabolic parameters, serum measures, SVF | Measurement of cytokine secretions, immune cell phenotyping, correlation CCL18 with CD4 T cells, lipolysis. Correlations and comparisons between the four metabolic groups | Table 1 |
2 | 26.1 | Obese and non-obese women | Global mRNA profiling in FACS sorted WAT cell populations and paired adipocyte samples | Expression of CCL18 receptor, IFN-γ and TGF-β in different adipose tissue resident cells | (33) |
3 | 42.7 | Obese IS and IR | Global WAT mRNA profiling, WAT phenotype, clinical metabolic parameters, serum measures | Correlation of CCL18 and CD4 | (34) |
4 | 33.1 | Non-obese and obese IS and IR | Global WAT mRNA profiling, WAT phenotype, clinical metabolic parameters | Correlation of CCL18 and CD4 | (35) |
5 | 43 | Obese (Before gastric bypass) | Global WAT mRNA profiling, WAT phenotype, clinical metabolic parameters | Correlation of CCL18 and CD4 | (36) |
6 | 26.2 | Non obese men with and without T2D | WAT mRNA, WAT phenotype, clinical metabolic parameters | Expression of CD4 T cell cytokines | (31) |