Positive association of triglyceride-glucose index with new-onset hypertension among adults: a national cohort study in China

Table 2 The association of TyG index with new-onset hypertension

TyG index	Total N	No. of events (incident rate^a)	Crude model		Model 1		Model 2
TyG index	Total N	No. of events (incident rate^a)	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
Quartiles
Q1 (≤ 8.1)	1150	208 (40.4)	Ref.		Ref.		Ref.
Q2 (> 8.1 to 8.5)	1150	291 (56.3)	1.45 (1.22–1.74)	< 0.001	1.27 (1.06–1.52)	0.010	1.29 (1.07–1.55)	0.006
Q3 (> 8.5 to 9.0)	1150	328 (62.5)	1.62 (1.37–1.93)	< 0.001	1.23 (1.03–1.47)	0.023	1.24 (1.03–1.49)	0.024
Q4 (> 9.0)	1150	384 (79.8)	2.21 (1.86–2.62)	< 0.001	1.47 (1.23–1.76)	< 0.001	1.50 (1.22–1.84)	< 0.001
P for trend				< 0.001		< 0.001		< 0.001
Categories
Q1 (≤ 8.1)	1150	208 (40.4)	Ref.		Ref.		Ref.
Q2-Q4 (> 8.1)	3450	1003 (65.9)	1.74 (1.50–2.02)	< 0.001	1.31 (1.12–1.53)	< 0.001	1.30 (1.11–1.53)	0.001
Continuous
Per 1.0 increase	4600	1211 (59.4)	1.39 (1.29–1.50)	< 0.001	1.14 (1.05–1.24)	0.002	1.17 (1.04–1.31)	0.007

Model1: adjusted for sex, age, BMI, WHR, SBP, DBP, smoking, and drinking
Model2 (Full model): Model1 + further adjusted for region, urban resistance, marital status, education, occupation, dietary intake of fat, protein and carbohydrate, diabetes mellitus, eGFR, BUN, uric acid, hsCRP, hemoglobin, total protein, LDL-C, TC, HbA1c, and FBI
TyG triglyceride-glucose, Q quartile, HR hazard ratio, CI confidence interval, Ref reference, BMI body mass index, WHR waist hip ratio, SBP systolic blood pressure, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, BUN blood urea nitrogen, hsCRP high sensitivity C reactive protein, LDL-C low density lipoprotein cholesterol, TC total cholesterol, HbA1c glycosylated hemoglobin A1c, FBI fasting blood insulin
^aIncident rate was presented as per 1000 person-years of follow-up

ISSN: 1475-2840