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Table 3 Association analyses for 9 promising SNPs with carotid atherosclerosis

From: Associations of genetic markers of diabetes mellitus with carotid atherosclerosis: a community-based case–control study

Candidate SNP

Typed SNP

Risk allele (genotype)

Reference allele (genotype)

Multivariable

Model 1

Model 2

ORa (95% CI)

ORb (95% CI)

rs4712523

rs4712524

AG or AA

GG

1.51+ (0.91–2.49)

rs4711389

rs1150777

AC

AA or CC

1.31 (0.88–1.93)

rs3751236

rs10842993

AG or GG

AA

1.55+ (0.98–2.45)

1.69* (1.08–2.66)

rs7983505

rs2858980

A

G

1.23 (0.92–1.64)

rs9515905

rs9583907

C

T

1.23 (0.94–1.61)

rs4924455

rs1077476

T

G

1.20 (0.95–1.52)

rs8026714

rs7180016

AA or GG

AG

1.30+ (0.94–1.79)

1.39* (1.02–1.91)

rs117267808

rs4383154

AA or GG

AG

1.68+ (0.99–2.84)

1.72* (1.03–2.88)

rs1421085

rs9937354

G

A

1.37* (1.01–1.87)

1.37* (1.01–1.86)

  1. aORs for each risk allele (genotype) were adjusted for age, sex, cigarette smoking, and hypertension
  2. bORs were obtained from the best fit model contained all genetic markers and were adjusted for age, sex, cigarette smoking, and hypertension
  3. +0.05 < p < 0.1; *0.005 < p < 0.05; **0.0001 < p < 0.005; ***p < 0.0001