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Fig. 2 | Cardiovascular Diabetology

Fig. 2

From: Systemic proinflammatory−profibrotic response in aortic stenosis patients with diabetes and its relationship with myocardial remodeling and clinical outcome

Fig. 2

Significantly upregulated plasma proteins in AS patients with diabetes on proteomic analysis. a Volcano plot identifying the significantly upregulated proteins (annotated in red) in the plasma proteome of diabetic AS patients. b Scatter plots comparing the plasma levels of differentially expressed proteins in AS patients with and without diabetes. All comparisons were adjusted for multiple testing with the Benjamini & Hochberg method, with adjusted p-values representing the false discovery rate. The horizontal bars for each group indicate median and interquartile range. adj, adjusted; AS, aortic stenosis; DM, diabetes mellitus; SELE, E-selectin; IL-1RT1, interleukin-1 receptor type 1; CTSD, cathepsin D; Gal-4, galectin-4; Gal-3, galectin-3; IL-1RT2, interleukin-1 receptor type 2; GDF-15, growth differentiation factor 15; ICAM-2, intercellular adhesion molecule 2; ITGB2, integrin beta-2

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Cardiovascular Diabetology

ISSN: 1475-2840