Table 2 Baseline characteristics according to categories of abnormal glucose metabolism based on IEC HbA1c-based definition
Variables | NGT N = 527 | Prediabetes N = 419 | DM N = 586 | P value |
|---|---|---|---|---|
Age (years) | 56.68 ± 9.93 | 60.63 ± 9.49 | 60.47 ± 9.14 |  < 0.0001 |
Female (%) | 150/527 (28.46) | 129/419 (30.79) | 209/586 (35.67) | 0.0312 |
Hypertension (%) | 304/527 (57.69) | 272/419 (64.92) | 437/586 (74.57) |  < 0.0001 |
Hyperlipidemia (%) | 270/527 (51.23) | 263/419 (62.77) | 382/586 (65.19) |  < 0.0001 |
Smoke (%) | 233/527 (44.21) | 170/419 (40.57) | 265/586 (45.22) | 0.3216 |
Alcohol (%) | 254/527 (48.20) | 190/419 (45.35) | 252/586 (43.00) | 0.2208 |
BMI (kg/m2) | 25.18 ± 3.02 | 25.73 ± 3.07 | 26.22 ± 3.26 |  < 0.0001 |
HR (bpm) | 68.66 ± 9.69 | 69.62 ± 10.38 | 71.30 ± 12.15 | 0.0002 |
SBP (mmHg) | 127.09 ± 16.24 | 126.45 ± 16.40 | 129.03 ± 16.37 | 0.0624 |
LVEF (%) | 64.77 ± 5.88 | 65.10 ± 6.68 | 64.45 ± 6.50 | 0.4097 |
NT-proBNP (pmol/L) | 537.40 (427.40, 693.90) | 550.95 (441.90, 703.20) | 547.15 (432.75, 737.35) | 0.4443 |
hsCRP (mg/L) | 1.01 (0.54, 1.88) | 1.36 (0.67, 2.64) | 1.56 (0.80, 3.08) |  < 0.0001 |
Cr (umol/L) | 72.94 (63.17, 82.35) | 73.25 (64.00, 80.95) | 72.60 (62.62, 82.38) | 0.8906 |
D_Dimer (ug/ml) | 0.26 (0.18, 0.37) | 0.28 (0.20, 0.39) | 0.29 (0.20, 0.41) | 0.0005 |
TC (mmol/L) | 4.22 (3.56, 4.87) | 4.14 (3.48, 4.86) | 4.04 (3.38, 4.78) | 0.1502 |
LDL (mmol/L) | 2.46 (1.93, 3.10) | 2.42 (1.80, 3.08) | 2.32 (1.84, 3.00) | 0.0953 |
HDL (mmol/L) | 1.10 (0.90, 1.30) | 1.08 (0.90, 1.28) | 1.02 (0.86, 1.20) |  < 0.0001 |
Lpa (mg/L) | 162.36 (65.18, 320.46) | 150.19 (64.42, 334.84) | 145.11 (53.53, 358.73) | 0.5735 |
Fasting glucose (mmol/L) | 5.03 ± 0.55 | 5.26 ± 0.57 | 7.12 ± 2.60 |  < 0.0001 |
HbA1c (%) | 5.64 ± 0.24 | 6.16 ± 0.13 | 7.26 ± 1.23 |  < 0.0001 |
Angiographic characteristics | ||||
 LM (%) | 21/527 (3.98) | 17/419 (4.06) | 16/586 (2.73) | 0.4138 |
 RCA (%) | 119/527 (22.58) | 82/419 (19.57) | 146/586 (24.91) | 0.1364 |
 LAD (%) | 349/527 (66.22) | 254/419 (60.62) | 388/586 (66.21) | 0.1240 |
 LCX (%) | 122/527 (23.15) | 107/419 (25.54) | 196/586 (33.45) | 0.0003 |
 Triple-vessel disease | 23/527 (4.36) | 9/419 (2.15) | 30/586 (5.12) | 0.0560 |