Table 1 Demographic characteristics of the study population
Variables | TyG index level | p | |||
|---|---|---|---|---|---|
Total (n = 1841) | (6.98 ≤ T1 < 8.42) (n = 615) | (8.42 ≤ T2 < 8.88) (n = 612) | (8.88 ≤ T3 < 10.88) (n = 614) | ||
Age, years | 58.3 ± 14.0 | 59.7 ± 14.3 | 58.0 ± 14.1 | 57.3 ± 13.7 | 0.010 |
Male, n (%) | 999 (54.3%) | 303 (49.3%) | 349 (57.0%) | 347 (56.5%) | 0.009 |
Duration of hypertension, years | 10.2 ± 8.4 | 9.3 ± 8.0 | 10.1 ± 8.3 | 10.3 ± 7.9 | 0.024 |
Newly diagnosed hypertension, n (%) | 125(6.8%) | 36 (5.9%) | 41 (6.7%) | 48(7.8%) | 0.227 |
Cardiovascular risks | |||||
Current smoker, n (%) | 520 (28.2%) | 146 (23.7%) | 179 (29.2%) | 195 (31.8%) | 0.006 |
Diabetes mellitus, n (%) | 480 (26.1%) | 72 (11.7%) | 143 (23.4%) | 265 (43.2%) | < 0.001 |
Baseline laboratory data | |||||
TC, mmol/L | 4.76 ± 1.03 | 4.45 ± 0.97 | 4.83 ± 0.98 | 5.01 ± 1.05 | < 0.001 |
TG, mmol/L | 1.63 ± 0.96 | 0.91 ± 0.22 | 1.43 ± 0.27 | 2.56 ± 1.11 | < 0.001 |
HDL-C, mmol/L | 1.14 ± 0.28 | 1.25 ± 0.31 | 1.12 ± 0.25 | 1.04 ± 0.24 | < 0.001 |
LDL-C, mmol/L | 2.61 ± 0.71 | 2.37 ± 0.66 | 2.70 ± 0.68 | 2.78 ± 0.73 | < 0.001 |
Hs-CRP, mmol/L | 1.00 (0.54–2.05) | 0.79 (0.39–1.50) | 1.01 (0.58–1.96) | 1.08 (0.65–2.71) | < 0.001 |
Lpa, mg/L | 144 (76.0–265) | 152 (85.0–299) | 147 (85.0–259) | 118 (61.0–234) | < 0.001 |
HbA1C, % | 6.12 ± 0.99 | 5.74 ± 0.45 | 6.05 ± 0.85 | 6.56 ± 1.30 | < 0.001 |
Creatinine, μmmol/L | 65.0 (55.0–77.0) | 65.0 (54.0–75.0) | 65.0 (56.0–79.0) | 66.0 (54.0–77.0) | 0.018 |
LVEF | 58.0 ± 4.65 | 58.0 ± 4.81 | 57.9 ± 4.93 | 58.1 ± 4.17 | 0.663 |
E/e’ | 8.88 ± 3.19 | 8.65 ± 3.32 | 8.86 ± 3.07 | 9.11 ± 3.17 | 0.040 |
CACS | 3.70 (0.00–119) | 0.70 (0.00–78.6) | 2.75 (0.00–126) | 8.70 (0.00–172) | 0.011 |
Outcome | |||||
OCAD, n (%) | 310 (16.8%) | 62 (10.1%) | 111 (18.1%) | 137 (22.3%) | < 0.001 |