Table 1 Anthropometric and metabolic characteristics of study subjects stratified into tertiles according to myocardial MrGlu values
|  | Myocardial MrGlu Tertile 1 Range 0.1–16.3 μmol/min/100 g (1) | Myocardial MrGlu Tertile 2 Range 16.4–26.29 μmol/min/100 g (2) | Myocardial MrGlu Tertile 3 Range 26.3–43 μmol/min/100 g (3) | P (1 vs 2)§ | P (1 vs 3)§ | P (2 vs 3)§ |
|---|---|---|---|---|---|---|
Sex (F/M) | 10/9 | 8/11 | 9/10 | 0.41 | 0.87 | 0.5 |
Age (years) | 53 ± 10 | 50 ± 12 | 48 ± 11 | 0.9 | 0.08 | 0.09 |
BMI (Kg/m2) | 32.5 ± 5 | 28.1 ± 4 | 29.2 ± 4 | 0.01 | 0.02 | 0.6 |
Waist circumference (cm) | 108 ± 12 | 98 ± 11 | 101 ± 10 | 0.5 | 0.4 | 0.7 |
Current smokers (%) | 47.4 | 52.9 | 31.6 | 0.8 | 0.09 | 0.2 |
Systolic blood pressure (mmHg) | 130 ± 12 | 124 ± 16 | 115 ± 15 | 0.5 | 0.03 | 0.1 |
Diastolic blood pressure (mmHg) | 79 ± 11 | 75 ± 11 | 75 ± 10 | 0.9 | 0.9 | 0.7 |
Heart Rate (bpm) | 78 ± 8 | 68 ± 7 | 68 ± 4 |  < 0.0001 |  < 0.0001 | 0.4 |
Fasting Plasma Glucose (mg/dL) | 131 ± 45 | 114 ± 35 | 100 ± 27 | 0.1 | 0.054 | 0.3 |
2-h post load plasma glucose (mg/dl) | 149 ± 15 | 132 ± 24 | 115 ± 13 | 0.1 |  < 0.0001 | 0.07 |
HbA1c (%) | 7.1 ± 1.2 | 6.5 ± 1.1 | 5.8 ± 1.1 | 0.2 | 0.01 | 0.1 |
Total Cholesterol (mg/dl) | 186 ± 37 | 196 ± 47 | 185 ± 29 | 0.2 | 0.7 | 0.3 |
HDL Cholesterol (mg/dl) | 45 ± 10 | 48 ± 8 | 49 ± 14 | 0.3 | 0.5 | 0.8 |
LDL Cholesterol (mg/dl) | 126 ± 36 | 127 ± 36 | 118 ± 28 | 0.6 | 0.9 | 0.3 |
Triglycerides (mg/dl) | 164 ± 74 | 119 ± 64 | 115 ± 60 | 0.2 | 0.1 | 0.7 |
NGT/Prediabetes/T2DM (n) | 1/4/14 | 6/6/7 | 13/1/5 | 0.005 | 0.001 | 0.2 |
Insulin-stimulated glucose disposal (mg/min x Kg FFM) | 3.16 ± 1.8 | 4.8 ± 3.1 | 8.4 ± 7.7 | 0.1 | 0.02 | 0.2 |
Antihypertensive therapy (%) | 58.3 | 35.3 | 16.7 | 0.4 | 0.04 | 0.1 |
Glucose-lowering therapy (%) Meftormin (%) | 70.6 | 33.3 | 26.3 | 0.02 | 0.01 | 0.8 |