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Table 1 Demographic data for the cohort of participants with T2DM (n = 804)

From: Association of biomarkers and risk scores with subclinical left ventricular dysfunction in patients with type 2 diabetes mellitus

Variable

Median [IQR] or n (%)

Age (years)

69 [65, 73]

Female gender

287 (35.7)

Diabetes duration (years)

10 [5, 17]

Overweight and obese

694 (86.4)

Prior MI

62 (7.7)

Prior stroke

48 (6)

History of smoking (current & ex)

386 (48)

BMI

29.3 [26.4, 33.2]

WHR

0.98 [0.92, 1.03]

SBP (mmHg)

131 [120, 142]

DBP (mmHg)

74 [67, 82]

HbA1c (%)

7.2 [6.5, 8.5]

Creatinine (mmol/L)

76 [65, 92]

eGFR (ml/min/1.73m2)

84.0 [70, 93]

HDL (mg/dL)

46 [39, 56]

NTpBNP (pg/mL)

50 [25, 101]

hs-TnT (pg/mL)

9.4 [6.8, 13.6]

Medications

 Beta-blocker

119 (14.8)

 ACEi/ARB

542 (67.4)

 Diuretics

159 (19.8)

 CCB

222 (27.6)

 Statin

552 (68.7)

 Anti-platelet

295 (36.7)

 Insulin

144 (18.0)

 Metformin

618 (77.1)

Echocardiographic parameters

 GLS (%)

−18.0 [-19.3, −16.7]

 E/e’

9.5 [7.8, 12]

 E/A

0.8 [0.68, 0.99]

 e’(cm/s)

7.0 [5.2, 8]

 LAVi (ml/m2)

32.7 [27.7, 39]

 LVMi (g/m2)

75.7 [64.1, 88.5]

Risk scores

 ARIC-HF 4 year (%)

8 [4, 12]

 WATCH-DM (points)

11 [9, 13]

  1. ACEi angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker, BMI body mass index, CCB calcium channel blocker, CKD chronic kidney disease, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, GLS global longitudinal strain, HbA1c haemoglobin A1 concentration, HDL high-density lipoprotein, hs-TnT high sensitivity troponin-T, LAVi left atrial volume indexed to body surface area, LVMi left ventricular mass indexed to body surface area, MI myocardial infarction, SBP systolic blood pressure, T2DM type 2 diabetes mellitus, WHR waist-to-hip ratio