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Table 4 Fine and Gray model evaluating the association between NT-ProBNP levels and cardiovascular mortality according to baseline HbA1c levels

From: NT-ProBNP and mortality across the spectrum of glucose tolerance in the general US population

Population

NT-ProBNP (pg/ml)

Cardiovascular mortality

HR

95% CI

p-value

Whole population

Per 1 SD

1.07

1.02–1.13

0.009

 < 100

1.00

Ref

 

100–299

1.57

1.17–2.10

0.003

 ≥ 300

2.08

1.47–2.93

 < 0.001

HbA1c < 5.7%

Per 1 SD

1.17

1.07–1.28

0.001

 < 100

1.00

Ref

 

100–299

1.35

0.87–2.10

0.186

 ≥ 300

1.79

1.05–3.05

0.032

HbA1c 5.7–6.4%

Per 1 SD

1.07

0.85–1.35

0.577

 < 100

1.00

Ref

 

100–299

2.15

1.20–3.85

0.010

 ≥ 300

3.04

1.47–6.28

0.003

Diabetes

Per 1 SD

1.03

0.96–1.10

0.406

 < 100

1.00

Ref

 

100–299

1.64

0.98–2.75

0.061

 ≥ 300

1.81

0.99–3.34

0.055

  1. Covariates included in model were age, sex, race-ethnicity, body mass index, education, cigarette smoke, total cholesterol, eGFR, blood pressure category, prevalent cardiovascular disease and alcohol consumption
  2. CI confidence interval, NT-ProBNP N-terminal pro-B natriuretic peptide