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Table 2 Association between baseline abdominal obesity indices and incident cardiovascular events in people with type 2 diabetes

From: Association between abdominal obesity indices and risk of cardiovascular events in Chinese populations with type 2 diabetes: a prospective cohort study

Indices

Event/

Total

Model 1

Model 2

Model 3

HR (95% CI)

P-value

HR (95% CI)

P-value

HR (95% CI)

P-value

WC

 Per 1 SD increase

289/2328

1.52 (1.37–1.69)

 < 0.001

1.59 (1.41–1.80)

 < 0.001

1.57(1.39–1.78)

 < 0.001

Quartiles

 Q1(≤ 84.10)

33/614

1.00

 

1.00

 

1.00

 

 Q2(84.20–90.00)

59/599

1.89 (1.23–2.89)

0.003

1.75 (1.14–2.68)

0.010

1.72 (1.12–2.65)

0.013

 Q3(90.10–98.00)

85/559

2.99 (2.00–4.47)

 < 0.001

2.95 (1.97–4.43)

 < 0.001

2.88 (1.92–4.32)

 < 0.001

 Q4(> 98.00)

112/556

4.05 (2.75–5.97)

 < 0.001

4.10 (2.74–6.12)

 < 0.001

3.92 (2.62–5.88)

 < 0.001

VAI

 Per 1 SD increase

289/2328

1.09 (1.05–1.13)

 < 0.001

1.11 (1.07–1.16)

 < 0.001

1.11 (1.06–1.16)

 < 0.001

Quartiles

 Q1(≤ 1.14)

22/582

1.00

 

1.00

 

1.00

 

 Q2(1.15–1.76)

66/582

3.11 (1.92–5.04)

 < 0.001

3.09 (1.90–5.02)

 < 0.001

3.03 (1.86–4.93)

 < 0.001

 Q3(1.77–2.66)

79/582

3.77 (2.35–6.04)

 < 0.001

4.10 (2.54–6.64)

 < 0.001

3.97 (2.45–6.44)

 < 0.001

 Q4(> 2.66)

122/582

6.11 (3.88–9.62)

 < 0.001

7.14 (4.46–11.41)

 < 0.001

6.88 (4.27–11.07)

 < 0.001

LAP

 Per 1 SD increase

289/2328

1.41 (1.32–1.50)

 < 0.001

1.47 (1.37–1.57)

 < 0.001

1.46 (1.36–1.57)

 < 0.001

Quartiles

 Q1(≤ 26.00)

24/583

1.00

 

1.00

 

1.00

 

 Q2(26.01–41.15)

56/581

2.40 (1.49–3.88)

 < 0.001

2.51 (1.55–4.06)

 < 0.001

2.50 (1.54–4.04)

 < 0.001

 Q3(41.16–65.00)

82/582

3.58 (2.27–5.64)

 < 0.001

3.71 (2.35–5.88)

 < 0.001

3.65 (2.30–5.80)

 < 0.001

 Q4(> 65.00)

127/582

5.84 (3.78–9.04)

 < 0.001

6.18 (3.96–9.63)

 < 0.001

6.03 (3.85–9.47)

 < 0.001

CVAI

 Per 1 SD increase

289/2328

1.87 (1.68–2.08)

 < 0.001

1.80 (1.60–2.04)

 < 0.001

1.78 (1.57–2.01)

 < 0.001

Quartiles

 Q1(≤ 96.58)

19/582

1.00

 

1.00

 

1.00

 

 Q2(96.59–121.59)

43/582

2.34 (1.37–4.02)

0.002

1.88 (1.09–3.24)

0.023

1.91 (1.11–3.30)

0.020

 Q3(121.60–146.38)

89/582

5.05 (3.08–8.29)

 < 0.001

3.81 (2.31–6.28)

 < 0.001

3.71 (2.24–6.15)

 < 0.001

 Q4(> 146.38)

138/582

8.14 (5.04–13.15)

 < 0.001

5.86 (3.61–9.53)

 < 0.001

5.67 (3.47–9.27)

 < 0.001

  1. Model 1: crude model; Model 2: adjusted for gender, age, ethnicity, education, smoking status, and drinking status; Model 3: adjusted for gender, age, ethnicity, education, smoking status, drinking status, low-density lipoprotein cholesterol, total cholesterol, fasting blood glucose, systolic blood pressure, diastolic blood pressure, physical activity, antidiabetic agents, and diabetes duration
  2. HR hazard ratio, CI confidence interval, SD standard deviation, WC waist circumference, VAI visceral adiposity index, LAP lipid accumulation product, CVAI Chinese visceral adiposity index
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Cardiovascular Diabetology

ISSN: 1475-2840