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Table 1 The baseline characteristics of subjects in the Kailuan Cohort

From: Triglyceride-glucose index and the risk of heart failure: Evidence from two large cohorts and a mendelian randomization analysis

  

TyG index

Characteristics

Total

Q1

Q2

Q3

Q4

3.60–8.18

8.19–8.57

8.58–9.05

9.06–12.51

Subjects (n)

95,996

23,997

24,000

24,001

23,998

TyG index

8.65 ± 0.69

7.85 ± 0.27

8.38 ± 0.11

8.79 ± 0.14

9.58 ± 0.46

Age, years

51.4 ± 12.5

50.2 ± 13.7

51.4 ± 12.7

52.1 ± 12.2

52.0 ± 11.4

Male, n (%)

76,364(79.6)

17,655(73.6)

18,994(79.1)

19,501(81.3)

20,214(84.2)

Height (cm)

167.4 ± 7.0

166.7 ± 7.0

167.5 ± 7.0

167.6 ± 7.0

167.9 ± 6.9

BMI (kg/m2)

25.0 ± 3.5

23.4 ± 3.2

24.6 ± 3.3

25.6 ± 3.3

26.4 ± 3.4

Completed high school, n (%)

18,746(19.5)

5673(23.6)

4483(18.7)

4448(18.5)

4142(17.3)

Income ≥ 800¥, n (%)

13,133(13.7)

3563(14.9)

3093(12.9)

3234(13.5)

3243(13.5)

Daily Smoker, n (%)

28,675(29.9)

6902(28.8)

6741(28.1)

7173(29.9)

7859(32.8)

Daily alcohol user, n (%)

16,725(17.4)

3891(16.2)

3834(16.0)

4125(17.2)

4875(20.3)

Activity physical activity, n (%)

13,935(14.5)

3654(15.2)

3356(14.0)

3535(14.7)

3390(14.1)

Systolic BP, mmHg

131 ± 21

124 ± 20

129 ± 20

132 ± 21

136 ± 21

Diastolic BP, mmHg

83 ± 12

80 ± 11

83 ± 11

85 ± 1

87 ± 12

FBG, mmol/L

5.47 ± 1.67

4.80 ± 0.68

5.09 ± 0.76

5.44 ± 1.11

6.54 ± 2.66

TC, mg/dL

190.9 ± 44.1

179.3 ± 35.6

190.2 ± 37.3

197.9 ± 39.0

196.4 ± 58.1

LDL-c, mg/dL

90.6 ± 35.2

84.3 ± 35.8

92.2 ± 33.3

94.7 ± 33.99

91.2 ± 36.7

HDL-c, mg/dL

59.8 ± 15.5

60.5 ± 15.7

60.3 ± 14.8

59.3 ± 15.1

59.0 ± 16.3

TG, mg/dL

112.4

(78.8-170.8)

62.0

(51.3–72.6)

97.4

(86.7–108.0)

137.2

(120.4-158.4)

245.1

(192.9–346.0)

hs-CRP, mg/dl

0.80

(0.30–2.16)

0.60

(0.21–1.84)

0.72

(0.29–1.99)

0.88

(0.33–2.16)

1.02

(0.40–2.61)

eGFR, mL/min/1.73m2

82.3 ± 25.7

85.8 ± 26.8

81.8 ± 25.4

81.4 ± 22.8

80.5 ± 27.2

Diabetes Mellitus, n (%)

8408(8.8)

223(0.9)

542(2.3)

1699(7.1)

5944(24.8)

Hypertension, n (%)

4,1072(42.8)

6847(28.5)

9651(40.2)

11,316(47.2)

13,258(55.3)

Anti-hypertensive drugs,

n (%)

9453(9.9)

1440(6.0)

1915(8.0)

2714(11.3)

3384(14.1)

Lipid-lowering drugs, n (%)

709(0.7)

81(0.3)

130(0.5)

168(0.7)

330(1.4)

Diabetes drugs, n (%)

2048(2.1)

121(0.5)

209(0.9)

442(1.8)

1273(5.3)

  1. Abbreviations: BMI: body mass index; BP: blood pressure; FBG: fasting blood glucose; TC: total cholesterol; LDL-c: low density lipoprotein cholesterol; HDL-c: low density lipoprotein cholesterol; TG: triglyceride; eGFR: estimated glomerular filtration rate; hs-CRP: high sensitivity C-reactive protein