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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: Neuregulin-4 attenuates diabetic cardiomyopathy by regulating autophagy via the AMPK/mTOR signalling pathway

Fig. 4

3-MA attenuates the protective effect of Nrg4 on diabetic cardiomyopathy. a Representative immunofluorescent images with TUNEL (green) and DAPI (blue) staining (original magnification ✕ 200). b Comparison of the apoptosis index in each group. c Stained with HE (original magnification ✕ 200). d Stained with Masson staining (original magnification ✕ 200). e Comparison of CVF in each group. f Representative echocardiographic images. g Quantitative analysis of LVEF, LVFS and LVEDV. Data are presented as the mean ± SD (n = 6 per group). Significant differences are depicted with *P < 0.05

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