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Table 4 Predictors of MACEs in the overall population by univariate and multivariate Cox regression analysis

From: Microvascular complications identify a specific coronary atherosclerotic phenotype in patients with type 2 diabetes mellitus

 

Univariate analysis

Multivariable analysis

HR (95% CI)

p

HR (95% CI)

p

Presence of ≥ 1 DMC

2.528 (1.261; 5.068)

0.009

2.891 (1.386; 6.030)

0.005

Smoking habit

2.146 (1.111; 4.144)

0.023

2.049 (1.003; 4.187)

0.049

Male sex

1.029 (0.498; 2.126)

0.939

0.944 (0.437; 2.038)

0.883

Age

0.969 (0.933; 1.005)

0.093

0.973 (0.936; 1.010)

0.153

LVEF on admission

1.016 (0.975; 1.059)

0.444

1.019 (0.979; 1.061)

0.352

Multivessel CAD

1.015 (0.531; 1.940)

0.964

0.965 (0.473; 1.970)

0.921

Diabetes duration (months since T2DM diagnosis)

0.998 (0.992; 1.004)

0.491

0.997 (0.991; 1.003)

0.319

  1. Bold values are reported for variables that are statistically significant (p < 0.05)
  2. MACEs major adverse cardiovascular events, DMC diabetic microvascular complications, LVEF left ventricle ejection fraction, CAD coronary artery disease, HR hazard ratio, CI confidence interval
  3. All variables in Table 1 and the presence of at least one of DMC have been tested to predict MACEs, although only variables with p-value < 0.050, age, male sex, EF on admission, multivessel CAD and diabetes duration (months since T2DM diagnosis) have been shown in the table. Variables that were significantly related to MACEs, along with age, male sex, EF on admission, multivessel CAD, diabetes duration (months since T2DM diagnosis) have been included in multivariate analysis