| Crude | Adjusted Model 1 | Adjusted Model 2 |
---|
OR or HR (95% CI) | p | OR or HR (95% CI) | p | HR (95% CI) | p |
---|
Previous MI at baseline* | | | | | | |
T1 vs T3 | 3.76 (1.12–17.08) | 0.03 | 7.84 (1.65–54.57) | 0.008 | | |
T1 vs T2 | 2.85 (0.93–10.64) | 0.07 | 4.56 (1.15–22.61) | 0.03 | | |
T2 vs T3 | 1.32 (0.28–6.86) | 0.72 | 1.72 (0.28–12.36) | 0.55 | | |
Z-score log[LTL] | 0.60 (0.36–0.99) | 0.05 | 0.31 (0.14–0.62) | 0.0007 | | |
CHD at follow-up | | | | | | |
T1 vs T3 | 2.55 (1.26–5.57) | 0.009 | 3.06 (1.37–7.43) | 0.006 | 3.14 (1.39–7.70) | 0.005 |
T1 vs T2 | 1.56 (0.87–2.85) | 0.14 | 1.84 (0.91–3.84) | 0.09 | 1.63 (0.80–3.39) | 0.18 |
T2 vs T3 | 1.63 (0.78–3.63) | 0.20 | 1.66 (0.72–4.08) | 0.24 | 1.92 (0.81–4.91) | 0.14 |
Z-score log[LTL] | 0.76 (0.58– 1.01) | 0.06 | 0.71 (0.52–0.96) | 0.03 | 0.73 (0.54–0.98) | 0.03 |
- *Odds ratio (OR) computed by logistic regression analyses and Hazard Ratio (HR) computed by Cox proportional hazards survival regression analysis for 1 SD of log[LTL] and for tertiles (T) of LTL distribution. T1 (short LTL), T2 (intermediate LTL), T3 (long LTL). Model 1: adjusted for sex, age, BMI, duration of diabetes, HbA1c, eGFR, UAC, tobacco smoking and use of ACE-Inhibitors, antihypertensive and lipid lowering drugs at baseline. Model 2: Model 1 plus adjustment for previous history of myocardial infarction at baseline. Number of participants with/without a previous myocardial infarction (MI) at baseline by LTL tertiles: 11/79 (T1), 4/82 (T2) and 3/81 (T3). Number of participants with/without incident CHD during follow-up by LTL tertiles: 25/65 (T1), 20/72 (T2) and 10/68 (T3)