Table 2 Comparison of clinical parameters between the MET group and the MET-DUL group before and after treatment [(\(\overline{x}\) ± s), n (%)]
Variables | MET | MET-DUL |
|---|---|---|
Number | ||
0-week | 30 | 30 |
12-week | 30 | 29 |
Male [n (%)] | ||
0-week | 17 (56.7%) | 18 (60.0%) |
12-week | 17 (56.7%) | 17 (58.6%) |
Age (year) | ||
0-week | 43.5 ± 4.4 | 42.9 ± 5.3 |
12-week | 43.5 ± 4.4 | 42.9 ± 5.2 |
BMI (kg/m2) | ||
0-week | 26.8 ± 2.7 | 27.1 ± 2.5 |
12-week | 26.7 ± 2.9 | 26.2 ± 2.6*Δ |
SBP (mmHg) | ||
0-week | 141.3 ± 14.2 | 139.4 ± 12.3 |
12-week | 140.5 ± 15.1 | 136.8 ± 13.4 |
DBP (mmHg) | ||
0-week | 94.1 ± 11.4 | 93.6 ± 12.2 |
12-week | 94.0 ± 12.2 | 92.8 ± 11.3 |
FPG (mmol/l) | ||
0-week | 7.4 ± 1.1 | 7.5 ± 0.9 |
12-week | 7.0 ± 1.2* | 6.9 ± 1.0* |
FCP (ng/ml) | ||
0-week | 1.2 ± 0.3 | 1.1 ± 0.2 |
12-week | 1.3 ± 0.2 | 1.3 ± 0.3 |
HbA1c (%; mmol/mol) | ||
0-week | 7.2 ± 0.2; 55.2 ± 1.6 | 7.1 ± 0.3; 54.1 ± 1.8 |
12-week | 6.8 ± 0.2; 50.8 ± 1.5* | 6.6 ± 0.2; 47.5 ± 1.6* |
TG (mmol/l) | ||
0-week | 2.2 ± 0.8 | 2.3 ± 0.9 |
12-week | 2.0 ± 0.9 | 1.9 ± 1.0 |
TCH (mmol/l) | ||
0-week | 5.7 ± 1.3 | 5.6 ± 1.2 |
12-week | 5.6 ± 1.2 | 5.5 ± 1.1 |
HDL-C (mmol/l) | ||
0-week | 1.4 ± 0.3 | 1.3 ± 0.2 |
12-week | 1.4 ± 0.4 | 1.4 ± 0.3 |
LDL-C (mmol/l) | ||
0-week | 3.5 ± 0.5 | 3.4 ± 0.3 |
12-week | 3.5 ± 0.4 | 3.2 ± 0.4 |
NO (μmol/l) | ||
0-week | 68.9 ± 14.7 | 71.6 ± 13.9 |
12-week | 74.6 ± 13.9 | 148.9 ± 18.6#☆ |
VEGF (pmol/ml) | ||
0-week | 211.7 ± 25.8 | 208.3 ± 26.7 |
12-week | 219.5 ± 22.7 | 222.7 ± 27.1 |
SDF-1α (pmol/ml) | ||
0-week | 2056.1 ± 512.3 | 1989.6 ± 531.7 |
12-week | 2079.4 ± 496.5 | 2098.5 ± 548.3 |
CRP (mg/dl) | ||
0-week | 5.8 ± 1.1 | 5.7 ± 1.3 |
12-week | 5.7 ± 1.0 | 3.2 ± 1.1*Δ |
TNF-α (pg/ml) | ||
0-week | 17.9 ± 7.8 | 16.4 ± 7.1 |
12-week | 15.6 ± 7.5 | 9.5 ± 5.8*Δ |
IL-6 (ng/l) | ||
0-week | 126.1 ± 32.3 | 135.6 ± 30.8 |
12-week | 113.6 ± 29.7 | 88.6 ± 19.6*Δ |
AGEs (ng/ml) | ||
0-week | 918.9 ± 104.5 | 922.4 ± 106.8 |
12-week | 883.6 ± 98.9 | 798.9 ± 88.4*Δ |
EPCs (/106 cell) | ||
0-week | 27.2 ± 12.3 | 26.1 ± 13.4 |
12-week | 28.9 ± 13.4 | 45.8 ± 11.6*Δ |
BaPWV (cm/s) | ||
0-week | 1587.4 ± 103.5 | 1576.7 ± 111.6 |
12-week | 1493.8 ± 99.4 | 1215.4 ± 103.8*Δ |
EPA (OD value) | ||
0-week | 0.53 ± 0.06 | 0.53 ± 0.08 |
12-week | 0.60 ± 0.07 | 0.92 ± 0.09#☆ |
EAA (cell numbers) | ||
0-week | 35.95 ± 9.73 | 36.82 ± 10.75 |
12-week | 36.23 ± 10.90 | 51.51 ± 11.92*☆ |
EMA (cell numbers) | ||
0-week | 17.67 ± 8.32 | 18.89 ± 8.81 |
12-week | 18.17 ± 9.06 | 30.93 ± 10.14*Δ |
ETF (μm) | ||
0-week | 3284.21 ± 245.46 | 3293.78 ± 248.73 |
12-week | 3325.46 ± 287.91 | 3672.82 ± 395.18#Δ |