Table 3 Distribution of study covariates and hospital outcomes of MEN with and without T2DM with infective endocarditis in Spain (2016–2020), before and after propensity score matching (PSM)
BEFORE PSM | AFTER PSM | |||||
|---|---|---|---|---|---|---|
T2DM | No T2DM | p-value | T2DM | No T2DM | p-value | |
N, (incidence per 100,000 men per year) | 1829 (23.29) | 4821 (8.77) | < 0.001 | 1829 | 1829 | NA |
Age, mean (SD) | 71.61 (9.88) | 67.99 (13.17) | < 0.001 | 71.61 (9.88) | 72.86 (11.07) | < 0.001 |
40–66 years old, n (%) | 543 (29.69) | 2066 (42.85) | < 0.001 | 543 (29.69) | 489 (26.74) | < 0.001 |
67–75 years old, n (%) | 590 (32.26) | 1147 (23.79) | 590 (32.26) | 519 (28.38) | ||
≥ 76 years old, n (%) | 696 (38.05) | 1608 (33.35) | 696 (38.05) | 821 (44.89) | ||
Acute renal disease, n (%) | 463 (25.31) | 1025 (21.26) | < 0.001 | 463 (25.31) | 452 (24.71) | 0.675 |
Chronic renal disease, n (%) | 514 (28.1) | 676 (14.02) | < 0.001 | 514 (28.1) | 457 (24.99) | 0.033 |
Congestive heart failure, n (%) | 294 (16.07) | 432 (8.96) | < 0.001 | 294 (16.07) | 275 (15.04) | 0.386 |
COPD, n (%) | 253 (13.83) | 448 (9.29) | < 0.001 | 253 (13.83) | 256 (14) | 0.886 |
Dementia, n (%) | 31 (1.69) | 76 (1.58) | 0.732 | 31 (1.69) | 30 (1.64) | 0.897 |
Atrial fibrillation, n (%) | 545 (29.8) | 1278 (26.51) | 0.007 | 545 (29.8) | 564 (30.84) | 0.494 |
COVID-19, n (%) | 6 (0.33) | 26 (0.54) | 0.266 | 6 (0.33) | 3 (0.16) | 0.317 |
Ischemic heart disease, n (%) | 506 (27.67) | 740 (15.35) | < 0.001 | 506 (27.67) | 477 (26.08) | 0.279 |
Previous aortic valve disease, n (%) | 483 (26.41) | 1505 (31.22) | < 0.001 | 483 (26.41) | 483 (26.41) | 0.999 |
Previous mitral valve disease, n (%) | 402 (21.98) | 1308 (27.13) | < 0.001 | 402 (21.98) | 383 (20.94) | 0.444 |
Previous pulmonic valve disease, n (%) | 2 (0.11) | 12 (0.25) | 0.268 | 2 (0.11) | 1 (0.05) | 0.564 |
Previous tricuspid valve disease, n (%) | 104 (5.69) | 342 (7.09) | 0.040 | 104 (5.69) | 88 (4.81) | 0.236 |
Prosthetic valve carriers, n (%) | 173 (9.46) | 426 (8.84) | 0.429 | 173 (9.46) | 163 (8.91) | 0.567 |
CCI index, mean (SD) | 1.47 (1.13) | 1.14 (1.07) | < 0.001 | 1.47 (1.13) | 1.39 (1.16) | 0.053 |
Periannular complications / atrioventricular block, n (%) | 122 (6.67) | 288 (5.97) | 0.292 | 122 (6.67) | 96 (5.25) | 0.069 |
Septic arterial embolism, n (%) | 67 (3.66) | 221 (4.58) | 0.099 | 67 (3.66) | 52 (2.84) | 0.162 |
Cardiogenic shock, n (%) | 35 (1.91) | 126 (2.61) | 0.097 | 35 (1.91) | 45 (2.46) | 0.258 |
Dialysis, n (%) | 118 (6.45) | 213 (4.42) | 0.001 | 118 (6.45) | 88 (4.81) | 0.031 |
Heart valve surgery (aortic, mitral, tricuspid, pulmonary), n (%) | 336 (18.37) | 1123 (23.29) | < 0.001 | 336 (18.37) | 320 (17.5) | 0.490 |
Mechanical ventilation, n (%) | 207 (11.32) | 545 (11.3) | 0.988 | 207 (11.32) | 192 (10.5) | 0.426 |
Pacemaker implantation, n (%) | 121 (6.62) | 244 (5.06) | 0.013 | 121 (6.62) | 87 (4.76) | 0.015 |
LOHS, Median (IQR) | 19 (25) | 20 (25) | 0.866 | 19 (25) | 19 (24) | 0.556 |
IHM, n (%) | 302 (16.51) | 740 (15.35) | 0.244 | 302 (16.51) | 333 (18.21) | 0.176 |