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Table 3 Summary of the CCL7 in kidney disease in this review article

From: CCL7 as a novel inflammatory mediator in cardiovascular disease, diabetes mellitus, and kidney disease

Kidney disease

References

ESRD

Exhibit mycobacterium tuberculosis-specific CCL7 expression

[62]

Nephrolithiasis

CCL7 in papillary tips, kidney urine, and bladder urine ↑

[63]

Nephritis

CCL7 ↑

Macrophage and T lymphocyte infiltration ↑

[64,65,66]

Kidney fibrosis

CCL7 ↑

CCL7 could be up-regulated by TGF-β1

[67, 68]

Acute kidney injury

CCL7 (B cell) ↑

Facilitate neutrophil and monocyte recruitment ↑

[69]

Kidney stone

Oxalate upregulates CCL7 expressions in the human renal proximal tubular epithelial cells

[70]

Urinary obstruction

Oncostatin M treatment upregulates CCL7 mRNA in kidney fibroblasts/ kidney tubular interstitial fibrosis ↑

[71,72,73]

Diabetic kidney disease

Urinary expressions CCL7 in type 1 diabetes ↑

[51]

  1. ESRD end-stage renal disease, TGF-β transforming growth factor-β