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Fig. 7 | Cardiovascular Diabetology

Fig. 7

From: Dapagliflozin reduces the vulnerability of rats with pulmonary arterial hypertension-induced right heart failure to ventricular arrhythmia by restoring calcium handling

Fig. 7

Assessment of the SCaS properties. a Representative image of the SCaS. b Ca2+ spark frequency. c Ca2+ spark amplitude. d Ca2+ spark width. e Ca2+ spark duration. f Ca2+ spark mass. g Ca2+ spark-mediated leakage. All parameters were recorded and quantitatively analysed from the RVCMs of the 4 groups of rats. Each point represents the result from a single RVCM. RVCM right ventricular cardiomyocyte, SCaS spontaneous Ca2+ sparks. n/N = 15/5 = cells/rats per group. The horizontal lines show the mean ± SEM. One-way ANOVA. *p < 0.05, **p < 0.001, ***p < 0.001

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Cardiovascular Diabetology

ISSN: 1475-2840