| Univariate | Model 1 | Model 2 | Matched model |
---|---|---|---|---|
HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |
Mortality | ||||
 Overall | ||||
  DPP4 inhibitor | Ref | Ref | Ref | Ref |
  SGLT2 inhibitor | 0.44 (0.37,0.52) | 0.62(0.52,0.74) | 0.67 (0.56,0.80) | 0.70 (0.56,0.89) |
  Both inhibitors | 0.49 (0.42,0.56) | 0.65 (0.56,0.74) | 0.71 (0.62,0.82) |  |
 Patients ≥ 75 years | ||||
  DPP4 inhibitor | Ref | Ref | Ref | Ref |
  SGLT2 inhibitor | 0.56 (0.45,0.69) | 0.59 (0.48,0.74) | 0.64 (0.52,0.80) | 0.68 (0.51,0.90) |
  Both inhibitors | 0.58 (0.49,0.69) | 0.63 (0.53,0.75) | 0.69 (0.58,0.82) |  |
HF readmission | ||||
 Overall | ||||
  DPP4 inhibitor | Ref | Ref | Ref | Ref |
  SGLT2 inhibitor | 0.43 (0.38,0.48) | 0.48 (0.42,0.54) | 0.50 (0.44,0.56) | 0.52 (0.45,0.61) |
  Both inhibitors | 0.49 (0.45,0.54) | 0.53 (0.49,0.59) | 0.56 (0.51,0.62) |  |
 Patients ≥ 75 years | ||||
  DPP4 inhibitor | Ref | Ref | Ref | Ref |
  SGLT2 inhibitor | 0.54 (0.46,0.63) | 0.53 (0.45,0.62) | 0.54 (0.46,0.64) | 0.59 (0.47,0.74) |
  Both inhibitors | 0.53 (0.46,0.60) | 0.52 (0.46,0.60) | 0.55 (0.48,0.62) |  |
All-cause readmission | ||||
 Overall | ||||
  DPP4 inhibitor | Ref | Ref | Ref | Ref |
  SGLT2 inhibitor | 0.63 (0.59,0.67) | 0.65 (0.61,0.69) | 0.68 (0.63,0.72) | 0.72 (0.66,0.79) |
  Both inhibitors | 0.74 (0.70,0.78) | 0.76 (0.72,0.80) | 0.78 (0.74,0.83) |  |
 Patients ≥ 75 years | ||||
  DPP4 inhibitor | Ref | Ref | Ref | Ref |
  SGLT2 inhibitor | 0.70 (0.64,0.77) | 0.69 (0.63,0.76) | 0.71 (0.64,0.78) | 0.76 (0.65,0.87) |
  Both inhibitors | 0.76 (0.71,0.82) | 0.75 (0.69,0.81) | 0.77 (0.71,0.83) |  |