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Table 1 Baseline characteristics of the patients stratified by the TyG index tertiles

From: Adjustment of the GRACE score by the triglyceride glucose index improves the prediction of clinical outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention

Variable

T1(n = 332)

T2 (n = 327)

T3 (n = 327)

P value

GRACE variables

    

Age, years

68.10 ± 11.89

66.65 ± 10.95

65.07 ± 11.24

0.003

SBP, mmHg

131.28 ± 19.81

133.17 ± 22.69

132.25 ± 21.66

0.525

 h, bpm

76.15 ± 14.41

78.15 ± 14.95

78.66 ± 14.96

0.071

Serum creatinine, umol/L

77.60 (65.55, 90.75)

78.10 (66.80, 92.70)

73.20 (61.10, 90.20)

0.046

CHF, n (%)

125 (37.7)

128 (39.1)

142 (43.4)

0.292

Previous MI, n (%)

15 (4.5)

21 (6.4)

17 (5.2)

0.548

ST-segment depression, n (%)

129 (38.9)

124 (37.9)

155 (47.4)

0.025

Elevated cardiac enzymes/markers, n (%)

210 (63.3)

221 (67.6)

232 (70.9)

0.108

GRACE score

110.61 ± 31.99

109.54 ± 29.91

109.30 ± 32.31

0.851

the TyG index

8.28 ± 0.29

8.96 ± 1.73

9.79 ± 0.47

<0.001

Female, n (%)

72 (21.7)

83 (25.4)

124 (37.9)

<0.001

BMI, kg/m2

23.58 ± 2.89

24.61 ± 2.78

24.77 ± 2.78

<0.001

Smoking, n (%)

181 (54.5)

187 (57.2)

173 (52.9)

0.539

Previous PCI, n (%)

30 (9.0)

29 (8.9)

24 (7.3)

0.689

COPD, n (%)

22 (6.6)

20 (6.1)

13 (4.0)

0.291

Hypertension, n (%)

208 (62.7)

217 (66.4)

214 (65.4)

0.582

Diabetes mellitus, n (%)

49 (14.8)

105 (32.1)

189 (57.8)

<0.001

AF, n (%)

27 (8.1)

20 (6.1)

19 (5.8)

0.431

Previous Stroke, n (%)

25 (7.5)

27 (8.3)

23 (7.0)

0.839

Laboratory measurements

    

cTnT, pg/mL

28.29 (10.73, 968.00)

30.10 (11.84, 652.60)

59.25 (13.36, 1006.60)

0.233

BNP, pg/mL

109.85 (45.03, 301.08)

103.50 (32.60, 287.30)

111.60 (38.10, 324.00)

0.337

FBG (mmol/L)

5.39 ± 1.18

6.41 ± 1.82

9.19 ± 4.03

<0.001

TG (mmol/L)

0.97 ± 0.28

1.63 ± 0.44

2.96 ± 1.68

<0.001

TC (mmol/L)

4.07 ± 1.07

4.50 ± 1.24

4.85 ± 1.23

<0.001

HDL-C (mmol/L)

1.22 ± 0.33

1.14 ± 0.28

1.10 ± 0.27

<0.001

LDL-C (mmol/L)

2.47 ± 0.81

2.81 ± 0.92

3.22 ± 2.86

<0.001

LVEF

55.16 ± 8.81

55.33 ± 8.74

54.22 ± 9.28

0.231

Diagnosis, n (%)

   

0.262

UA

165 (49.7)

157 (48.0)

143 (43.7)

 

NSTEMI

62 (18.7)

77 (23.5)

82 (25.1)

 

STEMI

105 (31.6)

93 (28.4)

102 (31.2)

 

Angiographic data

    

MVD, n (%)

202 (60.8)

228 (69.7)

239 (73.1)

0.002

LM, n (%)

11 (3.3)

23 (7.0)

20 (6.1)

0.091

Calcified lesions, n (%)

42 (12.7)

44 (13.5)

50 (15.3)

0.603

Thrombosis, n (%)

20 (60.0)

28 (8.6)

31 (9.5)

0.238

Long lesion, n (%)

131 (39.5)

153 (46.8)

170 (52.0)

0.005

CTO, n (%)

54 (16.3)

82 (25.1)

67 (20.5)

0.020

Number of stents

1.35 ± 0.77

1.47 ± 0.91

1.56 ± 0.94

0.008

Length of stents, mm

35.12 ± 23.70

38.71 ± 27.56

41.51 ± 28.00

0.008

bSS

11.00 (7.00, 18.00)

14.00 (8.00, 21.00)

14.50 (8.50, 20.50)

<0.001

rSS

2.00 (0.00, 6.00)

3.00 (0.00, 7.50)

3 (0.00, 8.00)

0.010

ICR, n (%)

198 (59.6)

220 (67.3)

236 (72.2)

0.003

Discharge medications

    

Aspirin, n (%)

322 (97.0)

320 (97.9)

319 (97.6)

0.770

P2Y12 receptor inhibitor, n (%)

328 (98.8)

324 (99.1)

322 (98.5)

0.775

Statins, n (%)

321 (96.7)

319 (97.6)

319 (97.6)

0.733

β-blockers, n (%)

218 (65.7)

231 (70.6)

238 (72.8)

0.124

ACEI/ARB, n (%)

132 (39.8)

149 (45.6)

135 (41.3)

0.295

Diuretics, n (%)

50 (15.1)

50 (15.3)

51 (15.6)

0.982

Insulin, n (%)

4 (1.2)

20 (6.1)

46 (14.1)

<0.001

Oral hypoglycemic agents, n (%)

22 (6.6)

77 (23.5)

123 (37.6)

<0.001

  1. The patients were divided into three groups in accordance with tertiles of the TyG index [T1 (TyG index ≤ 8.65), T2 (8.65 < TyG index ≤ 9.24), and T3 (TyG index > 9.24)]. GRACE score, Global Registry of Acute Coronary Events score; TyG index, the triglyceride-glucose index; BMI, body mass index; MI, myocardial infarction; PCI, percutaneous coronary intervention; COPD, chronic obstructive pulmonary disease; AF, atrial fibrillation; SBP, systolic blood pressure; HR, heart rate; CHF, congestive heart failure; BNP, brain natriuretic peptide; FBG, fasting blood glucose; TG, triglyceride; TC, total cholesterol; HDL-C, high density lipoprotein; LDL-C, low density lipoprotein; LVEF, left ventricular ejection fraction; UA, unstable angina; STEMI, ST-segment elevation myocardial infarction; NSTEMI, non-ST-segment elevation myocardial infarction; MVD, multivessel disease; LM, left main disease; CTO, chronic total occlusion; bSS, baseline SYNTAX score; rSS, residual SYNTAX score; ICR, incomplete revascularization; ACEI/ARB, angiotensin converting enzyme inhibitor/angiotensin receptor blocker. Data are presented as the mean ± SD, median (IQR) or n (%)