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Table 5 Multivariate Cox regression analyses for MACE

From: Triglyceride-glucose index in the prediction of adverse cardiovascular events in patients with premature coronary artery disease: a retrospective cohort study

TyG index

HR (95% CI)

Model 1

Model 2

Model 3

Per 1 Unit increase

1.97 (1.42–2.74)**

1.57 (1.07–2.29)*

1.94 (1.20–3.14)*

Per 1 SD increase

1.47 (1.22–1.76)**

1.29 (1.04–1.60)*

1.45 (1.11–1.91)*

Tertile 1

1 (Reference)

1 (Reference)

1 (Reference)

Tertile 2

1.94 (1.10–3.32)*

1.58 (0.91–2.75)

1.55 (0.87–2.78)

Tertile 3

2.70 (1.59–4.58)**

1.99 (1.12–3.52)*

2.17 (1.15–4.06)*

p for trend

 < 0.001

0.020

0.016

  1. Model 1: adjusted for age and gender
  2. Model 2: adjusted for variables with p-value < 0.05 in univariate analysis, including BMI, multivessel disease, current smoking, DM, hypertension, LDL-C, stains and hypoglycemic drugs
  3. Model 3: adjusted for age, gender, BMI, LVEF, admission for MI, multivessel disease, GS, current smoking, current drinking, FH-CAD, DM, hypertension, hyperlipidemia, TC, LDL-C, HDL-C, eGFR, UA, antiplatelet drugs, statins, beta-blockers, ACEI/ARB and hypoglycemic drugs
  4. MACE major adverse cardiovascular events, TyG index triglyceride-glucose index, HR hazard ratio, CI confidence interval, SD standard deviation
  5. p values in bold are < 0.05
  6. * p < 0.05
  7. ** p < 0.001