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Table 1 Baseline characteristics of the study population according to the occurrence of MACE

From: Triglyceride-glucose index in the prediction of adverse cardiovascular events in patients with premature coronary artery disease: a retrospective cohort study

Variables

Total (n = 526)

Without event (n = 425)

With event (n = 101)

p-value

General conditions

 Age (years)

44.48 ± 6.30

44.60 ± 6.20

44.01 ± 6.75

0.400

 Male, n (%)

316(60.1)

258 (60.7)

58 (57.4)

0.545

 BMI (kg/m2)

26.90 ± 3.36

26.78 ± 3.17

27.42 ± 4.04

0.138

 LVEF (%)

59.54 ± 9.99

59.56 ± 10.11

59.42 ± 9.53

0.893

 Admission for MI, n (%)

153 (29.1)

121 (28.5)

32 (31.7)

0.523

 GS

36.75 (22.00–61.00)

35.00 (21.50–60.00)

47.00 (25.00–64.00)

0.035

 Multivessel disease, n (%)

233 (44.3)

170 (40.0)

63 (62.4)

 < 0.001

Risk factors, n (%)

 Current smoking

148 (28.1)

111 (26.1)

37 (36.6)

0.035

 Current drinking

99 (18.8)

72 (16.9)

27 (26.7)

0.024

 FH-CAD

144 (27.4)

110 (25.9)

34 (33.7)

0.115

 DM

103 (19.6)

70 (16.5)

33 (32.7)

 < 0.001

 Hypertension

299 (56.8)

231 (54.4)

68 (67.3)

0.018

 Hyperlipidemia

176 (33.5)

140 (32.9)

36 (35.6)

0.605

Laboratory test

 FPG (mmol/L)

4.94 (4.51–5.88)

4.91 (4.47–5.65)

5.40 (4.64–7.29)

 < 0.001

 TC (mmol/L)

4.01 (3.36–4.83)

3.97 (3.34–4.79)

4.15 (3.49–4.94)

0.293

 TG (mmol/L)

1.43 (1.10–1.99)

1.41 (1.08–1.97)

1.58 (1.26–2.05)

0.027

 LDL-C (mmol/L)

2.49 (1.94–3.13)

2.45 (1.92–3.08)

2.65 (2.07–3.23)

0.029

 HDL-C (mmol/L)

1.18 ± 0.25

1.18 ± 0.26

1.15 ± 0.22

0.299

 eGFR (mL/min/1.73m2)

118.06 ± 25.99

117.76 ± 26.11

119.34 ± 25.54

0.584

 UA (μmol/L)

317.00(257.00–372.25)

320.00(258.50–371.00)

304.00(252.00–388.00)

0.637

Cardiovascular medications, n (%)

 Antiplatelet drugs

497 (94.5)

401 (94.4)

96 (95.0)

0.783

 Stains

501 (95.2)

408 (96.0)

93 (92.1)

0.160

 Beta-blockers

322(61.2)

265 (62.4)

57 (56.4)

0.273

 ACEI/ARB

246 (46.8)

196 (46.1)

50 (49.5)

0.540

 Hypoglycemic drugs

90 (17.1)

60 (14.1)

30 (29.7)

 < 0.001

 TyG index

8.76 ± 0.56

8.72 ± 0.57

8.94 ± 0.52

 < 0.001

  1. Data were given as mean ± SD, median with interquartile range or n (%)
  2. MACE major adverse cardiovascular events, BMI body mass index, LVEF left ventricle ejection fraction, MI myocardial infarction, GS Gensini score, FH-CAD family history of coronary artery disease, DM diabetes mellitus, FPG fasting plasma glucose, TC total cholesterol, TG triglyceride, LDL-C low-density lipoprotein-cholesterol, HDL-C high-density lipoprotein-cholesterol, eGFR estimated glomerular filtration rate, UA uric acid, ACEI angiotensin-converting enzyme inhibitors, ARB angiotensin receptor blockers, TyG index, triglyceride-glucose index
  3. p values in bold are < 0.05