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Fig. 7 | Cardiovascular Diabetology

Fig. 7

From: Glycated ACE2 reduces anti-remodeling effects of renin-angiotensin system inhibition in human diabetic hearts

Fig. 7

A Fibrosis (green) in heart specimens from nondiabetic patient, diabetic patient with poor glycemic control (mean HbA1c 8.1 ± 0.4%), and diabetic patient with good glycemic control (mean HbA1c 6.6 ± 0.2%). B Percent values of fibrosis (ZEN 2.5 pro software) in explanted hearts (HTX) at week 1 (Basal) and week 48 (Follow-up) from HTX in nondiabetic and diabetic patients. P < 0.05 vs nondiabetics, §P < 0.05 vs basal values. C Percent values of fibrosis (ZEN 2.5 pro software) in explanted hearts (HTX) at week 1 (Basal) and week 48 (Follow-up) from HTX, in the diabetic patients with good glycemic control (HbA1c < 7%) and diabetic patients with poor glycemic control (HbA1c ≥ 7%) *P < 0.05 vs diabetic patients in good glycemic control (< 7%), §P < 0.05 vs basal values

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Cardiovascular Diabetology

ISSN: 1475-2840