Table 2 Hazard Ratio (95% CI) for risks of CVD events, CHD, Stroke, CVD death at pre-defined levels of HbA1c
Outcome | No. of events/no. of patients | HbA1c (%) | |||||||
|---|---|---|---|---|---|---|---|---|---|
4.5 | 5.0 | 5.5 | 6.0 | 6.5 | 7.0 | 7.5 | 8.0 | ||
Primary outcome | |||||||||
CVD events | 1095/6685 | 0.78 (0.56–1.09) | 0.65 (0.53–0.81) | 0.68 (0.57–0.81) | 0.85 (0.78–0.92) | 0.95 (0.91–0.99) | Ref. | 1.05 (1.00–1.10) | 1.09 (1.00–1.21) |
Secondary outcomes | |||||||||
CHD | 916/6685 | 0.75 (0.52–1.10) | 0.70 (0.55–0.89) | 0.75 (0.62–0.91) | 0.89 (0.81–0.98) | 0.97 (0.92–1.02) | Ref. | 1.03 (0.97–1.09) | 1.05 (0.94–1.18) |
Stroke | 151/6685 | 1.00 (0.50–2.01) | 0.53 (0.31–0.91) | 0.46 (0.30–0.70) | 0.64 (0.54–0.77) | 0.82 (0.75–0.90) | Ref. | 1.20 (1.09–1.32) | 1.44 (1.19–1.76) |
CVD death | 144/6685 | 0.58 (0.22–1.53) | 0.48 (0.26–0.87) | 0.53 (0.33–0.85) | 0.74 (0.61–0.90) | 0.89 (0.81–0.99) | Ref. | 1.10 (0.99–1.24) | 1.22 (0.97–1.53) |