The effect of LDL-C status on the association between increased coronary artery calcium score and compositional plaque volume progression in statins-treated diabetic patients: evaluated using serial coronary CTAs

Table 4 Multivariate analysis of the association between annual changes in CACs and annual PVs changes according to LDL-C status

	LDL-C controlled	p	LDL-C uncontrolled	p
	β (95% CI)	p	β (95% CI)	p
Association with annual change in Agatston CACs
On per-patient level
TPV	0.650(0.347,0.952)	< 0.001	0.378(0.292,0.464)	< 0.001
CPV	0.169(0.048,0.290)	0.007	0.232(0.206,0.258)	< 0.001
NCPV	0.469(0.207,0.731)	0.001	0.144(0.063,0.226)	0.001
LD-NCPV	0.082(0.032,0.133)	0.002	0.086(0.066,0.106)	0.004
On per-plaque level
TPV	0.389(0.081,0.715)	0.014	0.413(0.286,0.539)	< 0.001
CPV	0.118(0.074,0.162)	< 0.001	0.226(0.165,0.286)	< 0.001
NCPV	0.268(− 0.037,0.573)	0.085	0.188(0.099,0.276)	< 0.001
LD-NCPV	0.056(− 0.007,0.119)	0.080	0.106(0.066,0.146)	< 0.001

The multivariate analysis models in different samples were adjusted for age, sex, BMI, hypertension, smoking history, drinking history, CAD family history, insulin, baseline CACs and total PV
Abbreviations are as in Table 3

ISSN: 1475-2840