Impact of red cell distribution width and red cell distribution width/albumin ratio on all-cause mortality in patients with type 2 diabetes and foot ulcers: a retrospective cohort study

Table 5 Improvement in discrimination and risk reclassification for all-cause mortality after the addition of RDW or RDW/ALB

Model	C-index (95% CI)	IDI (%) (95% CI)	P-value	NRI (%) (95% CI)	P-value
Base model 1	0.792 (0.745–0.839)	Ref	Ref	Ref	Ref
Base model 1 + RDW	0.804 (0.759–0.849)	2.7 (0.2–6.3)	0.02	23.4 (3.0–30.8)	0.03
Base model 2	0.783 (0.736–0.830)	Ref	Ref	Ref	Ref
Base model 2 + RDW/ALB	0.794 (0.747–0.841)	2.3 (0.4–5.5)	0.02	29.6 (11.0–40.0)	0.02

IDI and NRI were calculated at 32 months. Base model 1, adjusted for factors including age, BMI, SBP, severe DFUs, severe PAD, Hb, ALB, eGFR, cerebrovascular disease, diabetic retinopathy, diabetic peripheral neuropathy. Base model 2, adjusted for risk factors including age, BMI, SBP, severe DFUs, severe PAD, Hb, eGFR, cerebrovascular disease, diabetic retinopathy, diabetic peripheral neuropathy.
RDW red cell distribution width, ALB albumin, C-index Harrell’s concordance index, IDI integrated discrimination improvement, NRI net reclassification improvement index, Ref reference. Results with P value <0.05 were emphasized using bold letters.

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