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Table 1 Baseline characteristics of patients with pitavastatin vs. atorvastatin or rosuvastatin in KDH cohort

From: Impact of pitavastatin on new-onset diabetes mellitus compared to atorvastatin and rosuvastatin: a distributed network analysis of 10 real-world databases

 

Before PS adjustment

After PS adjustment

Pitavastatin (n = 1652)

Atorvastatin + rosuvastatin (n = 5787)

Std. diff

Pitavastatin (n = 1154)

Atorvastatin + rosuvastatin (n = 1876)

Std. diff

Age group

 20–24

< 0.3

0.3

− 0.01

< 0.4

< 0.2

− 0.03

 25–29

0.4

0.8

− 0.05

0.4

0.9

− 0.06

 30–34

1.0

1.7

− 0.06

1.0

1.3

− 0.02

 35–39

1.7

3.3

− 0.10

1.7

1.9

− 0.01

 40–44

4.6

4.7

0.00

4.9

5.2

− 0.01

 45–49

11.9

8.2

0.13

9.4

10.6

− 0.04

 50–54

23.2

12.9

0.27

17.4

21.0

− 0.09

 55–59

20.4

15.7

0.12

20.5

17.1

0.09

 60–64

14.5

14.1

0.01

16.0

15.4

0.02

 65–69

8.5

11.7

− 0.11

10.7

9.9

0.02

 70–74

7.1

10.7

− 0.13

9.0

8.3

0.03

 75–79

3.6

7.6

− 0.18

4.9

4.2

0.03

 80–84

1.8

5.2

− 0.19

2.5

2.1

0.03

 85–89

0.8

2.4

− 0.12

1.2

1.4

− 0.02

 90–94

< 0.3

0.7

− 0.06

< 0.4

0.5

− 0.04

Female

76.3

54.8

0.46

67.3

71.9

− 0.10

Charlson comorbidity indexa

0.52

0.71

− 0.19

0.56

0.52

0.03

Hyperlipidemia

17.5

17.3

0.00

17.1

17.5

− 0.01

Hypertensive disorder

26.7

29.0

− 0.05

27.1

26.0

0.02

Atrial fibrillation

1.0

1.6

− 0.05

1.4

1.1

0.03

Cerebrovascular disease

2.9

7.7

− 0.21

4.0

3.6

0.02

Heart failure

1.7

3.5

− 0.11

2.3

2.0

0.02

Ischemic heart disease

5.1

13.7

− 0.30

7.0

5.8

0.05

Chronic liver disease

< 0.3

0.2

0.00

< 0.4

< 0.2

0.02

Chronic obstructive lung disease

0.7

1.3

− 0.06

1.0

0.8

0.01

Renal impairment

1.2

2.1

− 0.07

1.6

1.3

0.02

Gastroesophageal reflux disease

6.2

5.8

0.01

6.0

5.8

0.01

Osteoarthritis

1.0

1.5

− 0.04

0.7

1.1

− 0.04

Dementia

1.0

1.5

− 0.04

0.7

1.1

− 0.04

Depressive disorder

0.5

2.3

− 0.15

0.8

0.9

− 0.01

Schizophrenia

1.7

2.3

− 0.04

1.7

1.8

− 0.01

Visual system disorder

0.4

0.1

0.06

0.4

< 0.2

0.08

Medication use

 RAS blocker

15.9

24.0

− 0.20

21.1

18.3

0.07

 Beta blocker

17.9

23.8

− 0.14

22.0

21.3

0.02

 Calcium channel blockers

10.9

16.0

− 0.15

13.5

11.9

0.05

 Diuretics

15.3

21.6

− 0.16

17.6

16.0

0.04

Antibiotics use

26.0

24.3

0.04

17.3

18.6

− 0.03

NSAIDs use

29.6

28.3

0.03

22.0

23.6

− 0.04

Drugs for acid related disorders

30.8

42.7

− 0.25

29.9

28.1

0.04

Drugs for obstructive airway diseases

3.0

5.1

− 0.11

3.1

3.6

− 0.02

Immunosuppressants

1.3

1.7

− 0.04

1.5

0.8

0.06

  1. PS, propensity score; RAS, renin-angiotensin system; NSAIDs, nonsteroidal anti-inflammatory drugs
  2. aRomano’s Adaptation of the Charlson Comorbidity Index was used and presented as the mean value. All other variables are presented as a percentage of the sample size