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Table 5 Associations between TyG index and CAD severity according to different glucose metabolism states

From: Triglyceride glucose index for the detection of the severity of coronary artery disease in different glucose metabolic states in patients with coronary heart disease: a RCSCD-TCM study in China

Glucose regulation state

Variables

Multi-vessel coronary artery disease

OR (95% CI)a

P-value

OR (95% CI)b

P-value

OR (95% CI)c

P-value

NGR

TyG index

1.828 (0.802–4.166)

0.151

1.747 (0.726–4.203)

0.213

1.797 (0.706–4.573)

0.219

T1

Reference

 

Reference

 

Reference

 

T2

1.292 (0.512–3.257)

0.588

1.227 (0.458–3.287)

0.684

1.329 (0.467–3.783)

0.594

T3

3.321 (0.619–17.820)

0.161

3.052 (0.529–17.608)

0.212

3.373 (0.545–25.628)

0.180

Pre-DM

TyG index

0.990 (0.623–1.574)

0.966

1.055 (0.658–1.691)

0.824

0.926 (0.565–1.517)

0.182

T1

Reference

 

Reference

 

Reference

 

T2

0.918 (0.540–1.562)

0.753

0.945 (0.553–1.616)

0.837

0.868 (0.449–1.509)

0.759

T3

0.825 (0.396–1.719)

0.608

0.905 (0.430–1.908)

0.794

0.791 (0.367–1.707)

0.616

DM

TyG index

1.646 (1.127–2.404)

0.010

1.721 (1.170–2.532)

0.006

1.717 (1.161–2.539)

0.007

T1

Reference

 

Reference

 

Reference

 

T2

1.191 (0.610 -2.327)

0.609

1.192 (0.609–2.334)

0.608

1.030 (0.513–2.069)

0.933

T3

2.185 (1.142–4.181)

0.018

2.273 (1.180–4.376)

0.014

2.105 (1.069–4.144)

0.031

  1. Compared with single-vessel CAD
  2. OR, odds ratios; CI, confidence interval; NGR, normal glucose regulation; Pre-DM, prediabetes mellitus; DM, diabetes mellitus
  3. aModel 1: unadjusted
  4. bModel 2: adjusted for age and sex;
  5. cModel 3: adjusted for age, sex, SBP, DBP, BMI, smoking, drinking, and antihypertensive, antilipidemic, and antiplatelet drug therapy