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Table 1 Baseline characteristics of participants by cumulative TyG index quartiles

From: Relationship of cumulative exposure to the triglyceride-glucose index with ischemic stroke: a 9-year prospective study in the Kailuan cohort

  Total Q1 Q2 Q3 Q4 P
Participants 54,098 13,524 13,525 13,525 13,524  
Age (years) 49.03 ± 11.84 44.88 ± 10.57 46.99 ± 11.50a 50.71 ± 11.89ab 53.54 ± 11.42abc  < 0.01
Male, N (%) 41,157 (76.08) 9561 (70.70) 10,782 (79.72) 10,506 (77.68) 10,308 (76.22)  < 0.01
BMI (kg/m2) 25.01 ± 3.16 24.03 ± 3.04 24.84 ± 3.14a 25.29 ± 3.10ab 25.87 ± 3.07abc  < 0.01
SBP (mmHg) 129.44 ± 16.88 123.71 ± 15.66 128.33 ± 15.64a 131.63 ± 16.93ab 134.07 ± 17.41abc  < 0.01
DBP (mmHg) 83.54 ± 9.22 81.19 ± 9.14 83.50 ± 8.86a 84.43 ± 9.21ab 85.06 ± 9.20abc  < 0.01
HDL-C (mmol/L) 1.54 ± 0.32 1.59 ± 0.32 1.55 ± 0.30a 1.53 ± 0.32ab 1.49 ± 0.33abc  < 0.01
LDL-C (mmol/L) 2.49 ± 0.64 2.33 ± 0.64 2.49 ± 0.60a 2.54 ± 0.62ab 2.62 ± 0.64abc  < 0.01
FBG (mmol/L) 5.54 ± 1.38 5.09 ± 0.68 5.35 ± 0.96a 5.58 ± 1.31ab 6.15 ± 1.99abc  < 0.01
TG (mmol/L) 1.34 (0.98–1.96) 0.97 (0.75–1.25) 1.32 (1.01–1.75)a 1.45 (1.07–2.19)ab 1.87 (1.37–2.72)abc  < 0.01
hs-CRP (mg/L) 1.45 (0.77–2.93) 1.35 (0.67–2.80) 1.34 (0.71–2.69)a 1.49 (0.80–2.98)ab 1.64 (0.92–3.19)abc  < 0.01
TyG index2006 8.64 ± 0.69 8.22 ± 0.53 8.56 ± 0.57a 8.74 ± 0.65ab 9.04 ± 0.70abc  < 0.01
TyG index2008 8.66 ± 0.68 8.19 ± 0.50 8.56 ± 0.51a 8.76 ± 0.61ab 9.15 ± 0.69abc  < 0.01
TyG index2010 8.69 ± 0.67 8.30 ± 0.51 8.61 ± 0.55a 8.77 ± 0.65ab 9.09 ± 0.70abc  < 0.01
Cum-TyG 34.93 ± 1.48 30.05 ± 1.62 33.23 ± 0.70a 35.88 ± 0.87ab 40.56 ± 2.61abc  < 0.01
Current smoking, N (%) 20,711 (38.28) 5314 (39.29) 5465 (40.41) 5111 (37.79)ab 4821 (35.65)abc  < 0.01
Current drinker, N (%) 19,167 (35.43) 4789 (35.4) 4952 (36.61) 4769 (35.26) 4657 (34.44)ab  < 0.01
Physical activity, N (%) 7833.0 (14.48) 1584 (11.71) 1621 (11.99) 2163 (15.99)ab 2465 (18.23)abc  < 0.01
Hypertension, N (%) 25,880 (47.84) 4649 (34.38) 6062 (44.82)a 7115 (52.61)ab 8054 (59.55)abc  < 0.01
Diabetes mellitus, N (%) 6022 (11.13) 470 (3.48) 930 (6.88)a 1605 (11.87)ab 3017 (22.31)abc  < 0.01
Antihypertensive drugs, N (%) 8397 (15.5) 1354 (10.01) 2007 (14.84)a 2371 (17.53)ab 2665 (19.71)abc  < 0.01
Hypoglycemic drugs, N (%) 3125 (5.78) 239 (1.77) 453 (3.35)a 772 (5.71)ab 1661 (12.3)abc  < 0.01
Lipid-lowering drugs, N (%) 905 (1.67) 123 (0.91) 163 (1.21)a 226 (1.67)ab 393 (2.91)abc  < 0.01
  1. P, comparison of baseline characteristics between different TyG index groups
  2. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, FBG fasting blood glucose, TG triglyceride, hs-CRP high-sensitivity C reactive protein, TyG index triglyceride-glucose index
  3. aP < 0.05, compare with Q1 group. bP < 0.05, compare with Q2 group. cP < 0.05, compare with Q3 group