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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Relative contributions of statin intensity, achieved low-density lipoprotein cholesterol level, and statin therapy duration to cardiovascular risk reduction in patients with type 2 diabetes: population based cohort study

Fig. 1

Cubic spline curve of adjusted hazard ratio for major cardiovascular events according to achieved LDL-C levels (mmol/L). Adjusted HR* (blue line) and 95% CI (shaded area) for major cardiovascular events according to on-treatment LDL-C levels with a reference of 2.6 mmol/L. The achieved LDL-C levels of the points at which 95% CI meets the reference line (HR = 1) are 1.9 mmol/L and 4.2 mmol/L. *Adjusted for age, sex, socioeconomic status, duration of diabetes, body mass index, fasting blood glucose, systolic blood pressure, creatinine, smoking, alcohol consumption, exercise, pre-existing cardiovascular disease (ischemic heart disease, ischemic stroke, and heart failure), and concurrent medications (anti-thrombotic agents, anti-hypertensive agents by class, and anti-diabetic agents by class)

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