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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Lower miR-21/ROS/HNE levels associate with lower glycemia after habit-intervention: DIAPASON study 1-year later

Fig. 1

miR-21 expression in plasma samples after 1 year of habit-intervention (HI). A Scatter dot plot of miR-21 expression at baseline and 1 year after habit-intervention in which miR-21 was normalised to cel-miR-39 expression using the comparative Ct method in a longitudinal cohort (at baseline, N = 531; at 1 year of HI, n = 207; paired miR21, n = 116). Wilcoxon Signed-Rank test for paired data, p < 0.0001. B Scatter dot plot of ROS extracellular release (measured by EPR instruments) in sera showing significant reduction after habit-intervention (ROS paired n = 48). Paired T-test, p = 0.03. C Scatter dot plot of plasma concentration of HNE (μg/mL) in the dysglycemic cohort (paired HNE n = 130). Wilcoxon Signed-Rank test for paired data, p < 0.0001. ****p < 0.0001; *p < 0.05.

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Cardiovascular Diabetology

ISSN: 1475-2840