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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: Diet-induced weight loss in obese/diabetic mice normalizes glucose metabolism and promotes functional recovery after stroke

Fig. 4

Stroke-induced astrocyte response in contralateral striatum of T2D mice is normalized by weight loss. a GFAP immunoreactivity in striatum after sham surgery. b GFAP immunoreactivity fold increase over sham in ipsilateral striatum after tMCAO. c GFAP immunoreactivity fold increase over sham in striatum contralateral to stroke lesion after tMCAO. Data are presented as mean ± SD. Brown–Forsythe and Welch ANOVA followed by Dunnett’s post hoc test; *p < 0.05. d Representative images of GFAP immunoreactivity in contralateral striatum after tMCAO. Group sizes: a non-T2D n = 5, T2D/Ob n = 4, T2D/WL n = 4. b, c Non-T2D n = 3, T2D/Ob n = 3, T2D/WL n = 3

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Cardiovascular Diabetology

ISSN: 1475-2840