Fig. 3

Hypoglycemia, glycemic variability and risk of cardiac arrhythmias. Incident rate ratio (95% CI) for cardiac arrhythmia (as defined by the study protocol) according to within-subject change in glycemic summaries (generalized linear mixed model). Note that no arrhythmias were detected during daytime hypoglycemia. *Risk of arrhythmia during an hour with occurrence of hypoglycemia defined as plasma glucose < 3.9 mmol/L compared with an hour of euglycemia with plasma glucose 3.9–10.0 mmol/L. Abbreviations: CV, coefficient of variation; NA, not applicable; SD, standard deviation