CAD-T2DM without prior MI or stroke | THEMIS-like population | PCI THEMIS-like population | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
All | < 65 years | [65–75] years | > 75 years | All | < 65 years | [65–75] years | > 75 years | All | < 65 years | [65–75] years | > 75 years | |
Composite outcome (MI, stroke & all-cause death) | 16.2 | 7.5 | 11.4 | 24.7 | 12.0 | 5.2 | 7.8 | 20.0 | 9.5 | 5.9 | 7.0 | 15.2 |
Myocardial infarction | 1.7 | 1.6 | 1.6 | 1.8 | 1.3 | 1.3 | 1.2 | 1.5 | 1.6 | 1.8 | 1.2 | 1.9 |
Ischemic stroke | 1.7 | 0.9 | 1.4 | 2.4 | 1.5 | 0.8 | 1.2 | 2.3 | 1.4 | 1.0 | 1.1 | 2.0 |
All-cause death | 13.6 | 5.2 | 8.9 | 21.9 | 9.7 | 3.3 | 5.7 | 17.3 | 6.8 | 3.3 | 4.8 | 12.0 |
Heart failure | 9.5 | 4.3 | 7.1 | 14.2 | 5.3 | 2.3 | 3.6 | 8.7 | 4.2 | 2.0 | 3.1 | 7.2 |
Major bleeding | 4.8 | 2.9 | 4.3 | 6.3 | 3.1 | 1.6 | 2.5 | 4.5 | 2.9 | 1.5 | 2.8 | 4.2 |
Intracranial bleeding | 0.6 | 0.3 | 0.5 | 0.8 | 0.4 | 0.2 | 0.3 | 0.7 | 0.4 | 0.1 | 0.4 | 0.5 |
Other bleeding with transfusion | 4.1 | 2.5 | 3.7 | 5.2 | 2.5 | 1.3 | 2.0 | 3.6 | 2.5 | 1.3 | 2.4 | 3.5 |
Fatal bleeding | 1.2 | 0.5 | 1.0 | 1.8 | 0.7 | 0.2 | 0.6 | 1.3 | 0.6 | 0.2 | 0.6 | 0.9 |