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Table 2 The lifetime risk of CVD up to age 95 adjusted for the competing risk of death for men and women at age 35, 45 and 55 according to individual fasting blood glucose variability (CV)

From: Visit-to-visit fasting blood glucose variability and lifetime risk of cardiovascular disease: a prospective study

FBG variability category (CV, %) Total Men Women
No. of CVD case/total Lifetime risk% (95%CI) P-value No. of CVD case/total Lifetime risk% (95%CI) P-value No. of CVD case/total Lifetime risk% (95%CI) P-value
35 years
 Low (< 6.19) 528/15339 26.3 (23.0, 29.5) Ref 455/11262 28.0 (24.5, 31.4) Ref 73/4077 17.8 (11.3, 24.2) Ref
 Intermediate (6.19–10.86) 603/15340 28.3 (25.5, 31.1) 0.357 547/11676 30.8 (27.9, 33.8) 0.214 56/3664 13.8 (9.6, 18.1) 0.316
 High (> 10.86) 758/15339 32.5 (28.9, 36.1) 0.013 688/12124 34.7 (30.9, 38.5) 0.010 70/3215 18.1 (10.6, 25.7) 0.942
45 years
 Low (< 6.26) 502/12713 26.0 (22.8, 29.3) Ref 430/9519 27.5 (24.1, 31.0) Ref 72/3194 17.9 (11.5, 24.2) Ref
 Intermediate (6.26%-11.03%) 584/12720 27.7 (25.0, 30.5) 0.443 528/9755 30.1 (27.2, 33.1) 0.269 56/2965 14.1 (9.9, 18.4) 0.335
 High (> 11.03%) 704/12716 32.1 (28.3, 35.9) 0.018 638/10042 34.4 (30.5, 38.4) 0.011 66/2674 18.0 (9.4, 26.5) 0.990
55 years
 Low (< 6.57%) 345/7041 24.6 (21.3, 28.0) Ref 294/5533 25.9 (22.3, 29.5) Ref 51/1508 16.4 (10.2, 22.5) Ref
 Intermediate (6.57–11.40) 408/7042 25.6 (22.8, 28.4) 0.655 364/5505 27.6 (24.5, 30.7) 0.468 44/1537 13.5 (9.1, 18.0) 0.464
 High (> 11.40) 468/7041 30.4 (26.3, 34.5) 0.032 423/5532 32.5 (28.2, 36.8) 0.020 45/1509 16.8 (7.8, 25.8) 0.937
  1. CVD Cardiovascular diseases, FBG Fasting blood glucose, CV Coefficient of variation
  2. Lifetime risk estimates represent the percentage of cohort participants who would experience a total CVD event from the index age to the end of follow-up if the last participant in the cohort were to die at the last age of follow-up (95 years)