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Table 2 The lifetime risk of CVD up to age 95 adjusted for the competing risk of death for men and women at age 35, 45 and 55 according to individual fasting blood glucose variability (CV)

From: Visit-to-visit fasting blood glucose variability and lifetime risk of cardiovascular disease: a prospective study

FBG variability category (CV, %)

Total

Men

Women

No. of CVD case/total

Lifetime risk% (95%CI)

P-value

No. of CVD case/total

Lifetime risk% (95%CI)

P-value

No. of CVD case/total

Lifetime risk% (95%CI)

P-value

35 years

 Low (< 6.19)

528/15339

26.3 (23.0, 29.5)

Ref

455/11262

28.0 (24.5, 31.4)

Ref

73/4077

17.8 (11.3, 24.2)

Ref

 Intermediate (6.19–10.86)

603/15340

28.3 (25.5, 31.1)

0.357

547/11676

30.8 (27.9, 33.8)

0.214

56/3664

13.8 (9.6, 18.1)

0.316

 High (> 10.86)

758/15339

32.5 (28.9, 36.1)

0.013

688/12124

34.7 (30.9, 38.5)

0.010

70/3215

18.1 (10.6, 25.7)

0.942

45 years

 Low (< 6.26)

502/12713

26.0 (22.8, 29.3)

Ref

430/9519

27.5 (24.1, 31.0)

Ref

72/3194

17.9 (11.5, 24.2)

Ref

 Intermediate (6.26%-11.03%)

584/12720

27.7 (25.0, 30.5)

0.443

528/9755

30.1 (27.2, 33.1)

0.269

56/2965

14.1 (9.9, 18.4)

0.335

 High (> 11.03%)

704/12716

32.1 (28.3, 35.9)

0.018

638/10042

34.4 (30.5, 38.4)

0.011

66/2674

18.0 (9.4, 26.5)

0.990

55 years

 Low (< 6.57%)

345/7041

24.6 (21.3, 28.0)

Ref

294/5533

25.9 (22.3, 29.5)

Ref

51/1508

16.4 (10.2, 22.5)

Ref

 Intermediate (6.57–11.40)

408/7042

25.6 (22.8, 28.4)

0.655

364/5505

27.6 (24.5, 30.7)

0.468

44/1537

13.5 (9.1, 18.0)

0.464

 High (> 11.40)

468/7041

30.4 (26.3, 34.5)

0.032

423/5532

32.5 (28.2, 36.8)

0.020

45/1509

16.8 (7.8, 25.8)

0.937

  1. CVD Cardiovascular diseases, FBG Fasting blood glucose, CV Coefficient of variation
  2. Lifetime risk estimates represent the percentage of cohort participants who would experience a total CVD event from the index age to the end of follow-up if the last participant in the cohort were to die at the last age of follow-up (95 years)