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Table 4 Determinants of LV contractile dysfunction in men with HFpEF

From: Effect of diabetes mellitus on the development of left ventricular contractile dysfunction in women with heart failure and preserved ejection fraction

 

GLS

GCS

GRS

 

Univariable

Multivariable

Univariable

Multivariable

Univariable

Multivariable

 

β

p-value

β

p-value

β

p-value

β

p-value

β

p-value

β

p-value

Age#, yrs

0.42

< 0.001

0.22

0.035

0.26

0.018

0.21

0.046

− 0.17

0.007

− 0.11

0.027

Obesity&

0.25

0.020

0.18

0.058

0.29

0.006

0.29

0.003

− 0.28

0.009

− 0.28

0.005

PP#, mmHg

− 0.05

0.614

  

− 0.07

0.552

  

0.08

0.446

  

HT

− 0.02

0.878

  

− 0.03

0.815

  

− 0.01

0.913

  

DM

0.20

0.060

  

0.18

0.102

  

− 0.07

0.511

  

CAD

0.33

0.002

0.20

0.037

0.17

0.111

  

− 0.14

0.189

  

NT-proBNP*, pg/mL

0.40

< 0.001

0.22

0.027

0.25

0.022

0.21

0.047

− 0.25

0.021

− 0.30

0.004

eGFR, mL/min/1.73m2

0.05

0.622

  

− 0.19

0.077

− 0.10

0.061

0.23

0.030

0.21

0.052

LVM, g

0.39

0.001

0.22

0.032

0.29

0.015

0.28

0.007

− 0.25

0.034

− 0.22

0.002

  1. β is adjusted regression coefficient. Variables with bold font indicate statistical significance in multivariable analysis. #. Changes in dependent variables per 10 units increase. &. Subjects with body mass index ≥ 25 kg/m2 were classified as obese group that proposed by the World Health Organization for Asian populations. *. NT-proBNP is log-transformed before being included in the regression analysis
  2. Abbreviations as listed in Table 3
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Cardiovascular Diabetology

ISSN: 1475-2840