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Table 4 Determinants of LV contractile dysfunction in men with HFpEF

From: Effect of diabetes mellitus on the development of left ventricular contractile dysfunction in women with heart failure and preserved ejection fraction

  GLS GCS GRS
  Univariable Multivariable Univariable Multivariable Univariable Multivariable
  β p-value β p-value β p-value β p-value β p-value β p-value
Age#, yrs 0.42 < 0.001 0.22 0.035 0.26 0.018 0.21 0.046 − 0.17 0.007 − 0.11 0.027
Obesity& 0.25 0.020 0.18 0.058 0.29 0.006 0.29 0.003 − 0.28 0.009 − 0.28 0.005
PP#, mmHg − 0.05 0.614    − 0.07 0.552    0.08 0.446   
HT − 0.02 0.878    − 0.03 0.815    − 0.01 0.913   
DM 0.20 0.060    0.18 0.102    − 0.07 0.511   
CAD 0.33 0.002 0.20 0.037 0.17 0.111    − 0.14 0.189   
NT-proBNP*, pg/mL 0.40 < 0.001 0.22 0.027 0.25 0.022 0.21 0.047 − 0.25 0.021 − 0.30 0.004
eGFR, mL/min/1.73m2 0.05 0.622    − 0.19 0.077 − 0.10 0.061 0.23 0.030 0.21 0.052
LVM, g 0.39 0.001 0.22 0.032 0.29 0.015 0.28 0.007 − 0.25 0.034 − 0.22 0.002
  1. β is adjusted regression coefficient. Variables with bold font indicate statistical significance in multivariable analysis. #. Changes in dependent variables per 10 units increase. &. Subjects with body mass index ≥ 25 kg/m2 were classified as obese group that proposed by the World Health Organization for Asian populations. *. NT-proBNP is log-transformed before being included in the regression analysis
  2. Abbreviations as listed in Table 3