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Table 1 Baseline characteristics of the study population by sex

From: Effect of diabetes mellitus on the development of left ventricular contractile dysfunction in women with heart failure and preserved ejection fraction

 

Women (n = 108)

Men (n = 116)

p-value

Age, yrs

63.3 ± 9.4

59.3 ± 11.3

0.019

BMI, kg/m2

23.1 ± 3.9

24.2 ± 3.3

0.043

Heart rate, beats/min

83.2 ± 14.4

79.2 ± 17.1

0.118

SBP, mmHg

126.4 ± 21.2

121.7 ± 21.9

0.181

DBP, mmHg

76.1 ± 13.5

73.7 ± 14.9

0.297

PP, mmHg

50.3 ± 17.2

48.0 ± 19.3

0.445

HF duration

 ≤ 1 yr

63 (58.3)

63 (54.3)

0.786

 > 1 and ≤ 5 yrs

27 (25.0)

30 (25.9)

 > 5 yrs

18 (16.7)

23 (19.8)

Cardiovascular comorbidities, n (%)

 DM

47 (43.5)

43 (37.1)

0.325

 HT

67 (62.0)

75 (64.7)

0.684

 CAD

19 (17.6)

35 (30.2)

0.028

Cardiovascular risk factors, n (%)

 Smoking

4 (3.7)

57 (49.1)

< 0.001

 Atrial fibrillation

24 (22.2)

24 (20.7)

0.780

 Dyslipidemia

34 (31.5)

26 (22.4)

0.126

Medications, n (%)

 Beta-blocker

71 (65.7)

75 (64.7)

0.865

 ACEI/ARB

77 (71.3)

86 (74.1)

0.633

 Diuretics

62 (57.4)

76 (65.5)

0.212

 CCB

15 (13.9)

16 (13.8)

0.983

 Anti-thrombotic agents

48 (44.4)

58 (50.0)

0.405

 Statins

29 (26.9)

46 (39.7)

0.042

Laboratory data

 NT-proBNP, pg/mL

1970 (698–3967)

1696 (586–3994)

0.004

 eGFR, mL/min/1.73m2

70.8 ± 26.5

76.9 ± 25.7

0.013

 TG, mmol/L

1.4 (0.9–1.9)

1.2 (0.8–1.6)

0.042

 TC, mmol/L

4.2 (3.4–5.1)

3.9 (3.2–4.5)

0.033

 HDL-C, mmol/L

1.1 (0.9–1.4)

1.0 (0.8–1.3)

0.181

  1. Data are presented as mean ± SD, media (Q1–Q3) or number (percentage)
  2. BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; PP: pulse pressure; HF: heart failure; DM: diabetes mellitus; HT: hypertension; CAD: coronary artery disease; AF: atrial fibrillation; ACEI: angiotensin converting enzyme inhibitor; ARB: angiotensin receptor blocker; CCB: calcium-channel blocker; NT-proBNP: amino-terminal pro-B-type natriuretic peptide; eGFR: estimated glomerular filtration rate; TG: triglycerides; TC: cholesterol; HDL-C: high-density lipoprotein cholesterol content