The association of hepatic steatosis and fibrosis with heart failure and mortality

Table 4 Hazard ratios and 95% confidence intervals for hospitalization for heart failure, all-cause mortality and cardiovascular mortality in patients with previous heart failure according to FLI score

	Model 1				Model 2		Model 3				Model 4
	Events (n)	HR	95% CI	p value	HR	95% CI	p value	HR	95% CI	p value	HR	95% CI	p value
hHF
FLI < 20	495	Ref.			Ref.			Ref.			Ref.
20 ≤ FLI < 60	677	1.059	0.943–1.189	0.334	1.123	0.982–1.283	0.090	1.113	0.973–1.272	0.118	1.040	0.909–1.190	0.567
FLI ≥ 60	250	1.141	0.980–1.328	0.090	1.469	1.203–1.793	< 0.001	1.428	1.168–1.746	< 0.001	1.259	1.027–1.543	0.027
All-cause mortality
FLI < 20	525	Ref.			Ref.			Ref.			Ref.
20 ≤ FLI < 60	563	0.823	0.730–0.926	0.001	1.151	1.001–1.325	0.049	1.141	0.991–1.313	0.067	1.054	0.915–1.215	0.466
FLI ≥ 60	190	0.803	0.680–0-948	0.010	1.836	1.480–2.277	< 0.001	1.792	1.441–2.228	< 0.001	1.541	1.236–1.922	< 0.001
CV mortality
FLI < 20	93	Ref.			Ref.			Ref.			Ref.
20 ≤ FLI < 60	114	0.942	0.717–1.239	0.671	1.355	0.982–1.870	0.064	1.338	0.968–1.850	0.077	1.210	0.874–1.675	0.250
FLI ≥ 60	34	0.812	0.549–1.203	0.300	1.937	1.170–3.206	0.010	1.850	1.112–3.077	0.018	1.535	0.918–2.568	0.102

CI confidence interval, CV mortality cardiovascular mortality, HR hazard ratio, hHF hospitalized heart failure
Model 1: crude
Model 2: age, sex and body weight
Model 3: model 2 + alcohol drinking, smoking, regular exercise, and income status
Model 4: model 3 + hypertension, diabetes mellitus, dyslipidemia, and estimated glomerular filtration rate

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