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Table 2 Unadjusted and adjusted hazard ratio of the association of sex with cardiovascular mortalitya stratified by type 2 diabetes mellitus status (n = 7443)

From: Association of sex-specific differences in lipoprotein(a) concentrations with cardiovascular mortality in individuals with type 2 diabetes mellitus

  No type 2 diabetes mellitus (n = 6988) Type 2 diabetes mellitus (n = 455)
Hazard ratio (95%-CI) p-value Hazard ratio (95%-CI) p-value
Model 1
 Men versus women 1.88 (1.58; 2.24) < 0.001 1.28 (0.89; 1.83) 0.178
Model 2
 Men versus women 1.94 (1.62; 2.31) < 0.001 1.41 (0.97; 2.04) 0.070
 Age (years) 1.15 (1.14; 1.16) < 0.001 1.12 (1.09; 1.15) < 0.001
 Body mass index (kg/m2) 1.06 (1.04; 1.08) < 0.001 1.00 (0.96; 1.04) 0.919
 Low-density lipoprotein cholesterol (mmol/L) 1.05 (0.96; 1.14) 0.315 1.02 (0.85; 1.25) 0.773
 Fasting status 1.28 (0.87; 1.88) 0.218 2.19 (0.68; 7.06) 0.191
Model 3
 Men versus women 1.94 (1.63; 2.32) < 0.001 1.53 (1.04; 2.24) 0.029
 Age (years) 1.15 (1.14; 1.16) < 0.001 1.12 (1.09; 1.15) < 0.001
 Body mass index (kg/m2) 1.06 (1.04; 1.08) < 0.001 1.00 (0.96; 1.04) 0.950
 Low-density lipoprotein cholesterol (mmol/L) 1.04 (0.95; 1.14) 0.377 1.02 (0.84; 1.24) 0.840
 Fasting status 1.27 (0.86; 1.88) 0.227 2.32 (0.72; 0.75) 0.161
 Lipoprotein(a) (100 mg/L) 1.01 (0.98; 1.05) 0.553 1.07 (1.01; 1.12) 0.012
  1. Data are reported as hazard ratios (95% confidence intervals [CI]) and p-values derived from Cox regression models. All models (including model 1) were also adjusted for study sample
  2. aCardiovascular mortality = ICD-10 codes: I10 to I79 in SHIP-0 and I10 to I99 in MONICA/KORA S3