Variables
|
DFS (n = 63)
|
NDFS (n = 30)
|
Healthy (n = 30)
|
pa
|
---|
Age (years) (mean ± SD)
|
66.57 ± 9.54
|
61.20 ± 9.40
|
64.83 ± 6.48
|
0.08
|
SBP (mmHg) (mean ± SD)
|
132.81 ± 13.81
|
130.83 ± 17.62
|
128.00 ± 10.38
|
0.39
|
DBP (mmHg) (mean ± SD)
|
71.14 ± 11.30b
|
75.33 ± 10.08
|
77.66 ± 11.04
|
0.02
|
Height (cm) (mean ± SD)
|
168.33 ± 7.19c
|
161.96 ± 20.12
|
163.93 ± 5.74
|
0.03
|
Weight (kg) (mean ± SD)
|
84.25 ± 14.10b
|
87.10 ± 27.82b
|
73.06 ± 9.92
|
0.005
|
BMI (kg/m2) (mean ± SD)
|
29.54 ± 4.23
|
30.78 ± 6.67
|
28.08 ± 4.19
|
0.11
|
RHI (mean ± SD)
|
1.60 ± 0.33bc
|
2.01 ± 0.69
|
2.20 ± 0.38
|
< 0.0005
|
MMSE (mean ± SD)
|
26.77 ± 3.44
|
27.03 ± 2.53
|
27.96 ± 1.24
|
0.16
|
MMSE corrected for age (mean ± SD)
|
26.57 ± 3.33b
|
27.16 ± 2.38
|
28.14 ± 1.15
|
0.03
|
HbA1c (%) (mean ± SD)
|
8.07 ± 1.26
|
7.74 ± 1.71
|
–
|
0.29
|
RMSDD (ms) (mean ± SD)
|
81.46 ± 95.22
|
46.23 ± 53.93
|
86.11 ± 74.04
|
0.10
|
SDNN/5 min (ms) (mean ± SD)
|
66.39 ± 23.97
|
59.40 ± 16.19
|
71.75 ± 22.52
|
0.09
|
SD (ms) (mean ± SD)
|
87.83 ± 50.65
|
85.69 ± 37.72
|
101.38 ± 47.07
|
0.34
|
LF% (mean ± SD)
|
19.63 ± 11.08
|
24.06 ± 13.64
|
55.35 ± 222.94
|
0.33
|
HF% (mean ± SD)
|
21.23 ± 14.68c
|
11.10 ± 11.58
|
14.70 ± 11.15
|
0.002
|
LF/HF (mean ± SD)
|
1.63 ± 1.66c
|
3.18 ± 2.82b
|
1.07 ± 0.44
|
< 0.0005
|
Omentin-1 (ng/mL) (mean ± SD)
|
18.95 ± 3.60bc
|
21.80 ± 5.79b
|
31.16 ± 4.53
|
< 0.0005
|
Vaspine (mean ± SD)
|
0.20 ± 0.05
|
0.21 ± 0.58
|
0.19 ± 0.03
|
0.23
|
- SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; RHI, reactive hyperemia index; MMSE, Mini Mental State Examination; RMSSD, root mean square of the successive differences in 5 min; SDNN, standard deviation of the NN (R-R) intervals; SD, standard deviation; LF, low frequency; HF, high frequency; LF/HF, low frequency/high frequency
- ap, intergroup differences among patient groups, univariate analysis of variance (ANOVA) and post hoc analysis with the Tukey test to determine pairwise intragroup differences
- bvs healthy subjects, cvs NDFS