Prognostic value of fibrinogen in patients with coronary artery disease and prediabetes or diabetes following percutaneous coronary intervention: 5-year findings from a large cohort study

Table 4 Predictive value of the FIB level for all-cause death and cardiac death in univariate and multivariate analysis

Variables	Events/subjects	Univariate analysis		Multivariate analysis
Variables	Events/subjects	Hazard ratio (95% CI)	P value	Hazard ratio (95% CI)	P value
All-cause death	214/6140
FIB (per 1-unit increase)		1.36 (1.20–1.55)	< 0.001	1.23 (1.07–1.42)	0.004
FIB-L	43/2069	Reference	–	Reference	–
FIB-M	75/2033	1.81 (1.24–2.63)	0.002	1.72 (1.18–2.51)	0.005
FIB-H	96/2038	2.35 (1.64–3.36)	< 0.001	1.86 (1.28–2.69)	0.001
Cardiac death	127/6140
FIB (per 1-unit increase)		1.46 (1.25–1.71)	< 0.001	1.31 (1.10–1.55)	0.003
FIB-L	28/2069	Reference	–	Reference	–
FIB-M	36/2033	1.33 (0.81–2.18)	0.259	1.26 (0.76–2.07)	0.369
FIB-H	63/2038	2.36 (1.51–3.68)	< 0.001	1.82 (1.15–2.89)	0.011

Model adjusted for age, sex, BMI, hypertension, diabetes, family history of CAD, prior PCI/CABG, LVEF, LDL-C, creatine, DES implantation, clopidogrel, ACEI/ARB
CI confidence interval, FIB fibrinogen

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