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Table 4 Predictive value of the FIB level for all-cause death and cardiac death in univariate and multivariate analysis

From: Prognostic value of fibrinogen in patients with coronary artery disease and prediabetes or diabetes following percutaneous coronary intervention: 5-year findings from a large cohort study

Variables

Events/subjects

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

P value

Hazard ratio (95% CI)

P value

All-cause death

214/6140

    

FIB (per 1-unit increase)

 

1.36 (1.20–1.55)

 < 0.001

1.23 (1.07–1.42)

0.004

FIB-L

43/2069

Reference

–

Reference

–

FIB-M

75/2033

1.81 (1.24–2.63)

0.002

1.72 (1.18–2.51)

0.005

FIB-H

96/2038

2.35 (1.64–3.36)

 < 0.001

1.86 (1.28–2.69)

0.001

Cardiac death

127/6140

    

FIB (per 1-unit increase)

 

1.46 (1.25–1.71)

 < 0.001

1.31 (1.10–1.55)

0.003

FIB-L

28/2069

Reference

–

Reference

–

FIB-M

36/2033

1.33 (0.81–2.18)

0.259

1.26 (0.76–2.07)

0.369

FIB-H

63/2038

2.36 (1.51–3.68)

 < 0.001

1.82 (1.15–2.89)

0.011

  1. Model adjusted for age, sex, BMI, hypertension, diabetes, family history of CAD, prior PCI/CABG, LVEF, LDL-C, creatine, DES implantation, clopidogrel, ACEI/ARB
  2. CI confidence interval, FIB fibrinogen