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Table 4 Predictive value of the FIB level for all-cause death and cardiac death in univariate and multivariate analysis

From: Prognostic value of fibrinogen in patients with coronary artery disease and prediabetes or diabetes following percutaneous coronary intervention: 5-year findings from a large cohort study

Variables Events/subjects Univariate analysis Multivariate analysis
Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
All-cause death 214/6140     
FIB (per 1-unit increase)   1.36 (1.20–1.55)  < 0.001 1.23 (1.07–1.42) 0.004
FIB-L 43/2069 Reference Reference
FIB-M 75/2033 1.81 (1.24–2.63) 0.002 1.72 (1.18–2.51) 0.005
FIB-H 96/2038 2.35 (1.64–3.36)  < 0.001 1.86 (1.28–2.69) 0.001
Cardiac death 127/6140     
FIB (per 1-unit increase)   1.46 (1.25–1.71)  < 0.001 1.31 (1.10–1.55) 0.003
FIB-L 28/2069 Reference Reference
FIB-M 36/2033 1.33 (0.81–2.18) 0.259 1.26 (0.76–2.07) 0.369
FIB-H 63/2038 2.36 (1.51–3.68)  < 0.001 1.82 (1.15–2.89) 0.011
  1. Model adjusted for age, sex, BMI, hypertension, diabetes, family history of CAD, prior PCI/CABG, LVEF, LDL-C, creatine, DES implantation, clopidogrel, ACEI/ARB
  2. CI confidence interval, FIB fibrinogen