Table 1 Serum and biochemical indicators of Ang II rats treated with vehicle or DAPA for 4 weeks
CTL | CTL + DAPA | Ang II | Ang II + DAPA | |
|---|---|---|---|---|
Glu (mM) | 8.29 ± 1.29 | 8.33 ± 1.28 | 8.09 ± 1.12 | 8.05 ± 1.17 |
INS (pg/ml) | 223 ± 38.94 | 224.53 ± 66.16 | 205.95 ± 49.33 | 215.59 ± 43.51 |
TC (mM) | 1.8 ± 0.2 | 1.6 ± 0.37 | 1.98 ± 0.48 | 1.85 ± 0.27 |
TG (mM) | 1.14 ± 0.49 | 1.08 ± 0.46 | 1.31 ± 0.46 | 1.22 ± 0.56 |
LDL-C (mM) | 0.35 ± 0.1 | 0.36 ± 0.09 | 0.35 ± 0.12 | 0.38 ± 0.07 |
HDL-C (mM) | 0.53 ± 0.16 | 0.57 ± 0.05 | 0.51 ± 0.19 | 0.59 ± 0.1 |
ALT (U/I) | 53.67 ± 8.59 | 61 ± 14.3 | 59.5 ± 7.61 | 52.33 ± 6.62 |
AST (U/I) | 244.09 ± 10.05 | 246.16 ± 38.39 | 229.17 ± 17.41 | 236 ± 12.18 |
CK (U/I) | 331.14 ± 11.81 | 327.08 ± 15.24 | 317.88 ± 18.12 | 321.81 ± 15.85 |
CK-MB (U/I) | 338.28 ± 13.79 | 337.41 ± 15.76 | 318.38 ± 20.62 | 326.69 ± 16.81 |
LDH (U/I) | 360.22 ± 13.26 | 359.74 ± 13.15 | 340.61 ± 24.75 | 354.96 ± 14.97 |
BUN (mM) | 6.61 ± 1.43 | 6.88 ± 1.76 | 7.84 ± 2.13 | 8.64 ± 2.05 |
SCr (μmol/l) | 18.12 ± 3.32 | 19.72 ± 2.89 | 20.05 ± 4.59 | 18.48 ± 2.59 |
UA (μmol/l) | 11.3 ± 7.12 | 13.38 ± 5.86 | 8.22 ± 3.5 | 7.57 ± 3.95 |