Change in triglyceride-glucose index predicts the risk of cardiovascular disease in the general population: a prospective cohort study

Table 3 Reclassification and discrimination statistics for changes in TyG index

	C statistics		IDI		Category-free NRI
	Estimate (95% CI)	P	Estimate (95% CI), %	P	Estimate (95% CI), %	P
CVD
Conventional model^a	0.739 (0.731–0.748)		Reference		Reference
Conventional model + changes in TyG index	0.742 (0.733–0.751)	0.0097	0.09 (0.05–0.13)	< 0.0001	12.58 (8.61–16.56)	< 0.0001
Stroke
Conventional model^a	0.740 (0.730–0.750)		Reference		Reference
Conventional model + changes in TyG index	0.742 (0.732–0.752)	0.0435	0.06 (0.02–0.09)	0.0010	10.83 (6.40–15.26)	< 0.0001
MI
Conventional model^*	0.749 (0.731–0.766)		Reference		Reference
Conventional model + changes in TyG index	0.752 (0.735–0.770)	0.0412	0.03 (0.01–0.05)	0.0365	16.69 (8.26–25.12)	0.0001

CVD cardiovascular disease, IDI integrated discrimination improvement, MI myocardial infarction, NRI net reclassification index, TyG index triglyceride-glucose index
^aConventional model was adjusted for age, sex, TyG index, education, income, smoking status, drinking status, physical activity, body mass index, systolic blood pressure, diastolic blood pressure, a history of hypertension, diabetes mellitus, and dyslipidemia, antidiabetic agents, lipid-lowering agents, antihypertensive agents, high-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and high-sensitivity C-reactive protein at baseline

ISSN: 1475-2840