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Table 2 HR and 95% CI for the association between changes in TyG index from 2006 to 2010 and cardiovascular diseases and its subtypes

From: Change in triglyceride-glucose index predicts the risk of cardiovascular disease in the general population: a prospective cohort study

 

Quartiles of changes in TyG index

P for trend

 

Q1 (< − 0.31)

Q2 (− 0.31 to 0.05)

Q3 (0.05–0.41)

Q4 (≥ 0.41)

CVD

     

 Case, n (%)

585 (3.75)

594 (3.81)

646 (4.14)

705 (4.52)

 

 Incidence rate, per 1000 person-y

5.54 (5.11–6.01)

5.65 (5.21–6.12)

6.17 (5.71–6.66)

6.73 (6.25–7.24)

 

 Model 1

Reference

1.18 (1.06–1.32)

1.26 (1.12–1.42)

1.42 (1.26–1.60)

 < 0.0001

 Model 2

Reference

1.17 (1.04–1.30)

1.24 (1.11–1.40)

1.37 (1.21–1.54)

 < 0.0001

Stroke

     

 Case, n (%)

465 (2.98)

473 (3.03)

528 (3.38)

552 (3.54)

 

 Incidence rate, per 1000 person-y

4.39 (4.01–4.80)

4.48 (4.10–4.91)

5.03 (4.62–5.47)

5.24 (4.82–5.70)

 

 Model 1

Reference

1.24 (1.08–1.41)

1.27 (1.11–1.47)

1.44 (1.24–1.66)

 < 0.0001

 Model 2

Reference

1.22 (1.07–1.40)

1.26 (1.09–1.45)

1.38 (1.19–1.60)

 < 0.0001

MI

     

 Case, n (%)

126 (0.81)

126 (0.81)

128 (0.82)

165 (1.06)

 

 Incidence rate, per 1000 person-y

1.18 (0.99–1.40)

1.19 (1.00–1.41)

1.21 (1.02–1.44)

1.55 (1.33–1.81)

 

 Model 1

Reference

1.05 (0.82–1.34)

1.22 (0.95–1.57)

1.41 (1.09–1.82)

0.0050

 Model 2

Reference

1.02 (0.80–1.30)

1.19 (0.93–1.53)

1.36 (1.05–1.76)

0.0115

  1. Model 1: adjusted for age, sex, and TyG index at baseline. Model 2: further adjusted for education, income, smoking status, drinking status, physical activity, body mass index, systolic blood pressure, diastolic blood pressure, a history of hypertension, diabetes mellitus, and dyslipidemia, antidiabetic agents, lipid-lowering agents, antihypertensive agents, high-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and high-sensitivity C-reactive protein at baseline
  2. CI confidence interval, CVD cardiovascular disease, MI mypcardial infarction, HR hazard ratio, TyG index triglyceride-glucose index